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Proteintech
CXCR7 Monoclonal Antibody (4C3D7)
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Product Details
60216-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
4C3D7
Immunogen
CXCR7 Fusion Protein Ag14247 (273-362 aa encoded by BC036661)
Conjugate
Form
Liquid
Concentration
1.27 mg/mL
Amount
190.5 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody recognizes endogenous CXCR7, which has an experimentally determined molecular weight of 50 kDa.
Immunogen sequence: LLDIFSILH YIPFTCRLEH ALFTALHVTQ CLSLVHCCVN PVLYSFINRN YRYELMKAFI FKYSAKTGLT KLIDASRVSE TEYSALEQST K (273-362 aa encoded by BC036661)
Target Information
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Atypical chemokine receptor 3; C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 7; CC motif chemokine; CCmotif chemokine; chemokine; chemokine (C-X-C motif) receptor 7; Chemokine orphan receptor 1; CXC; CXC motif chemokine; CXC-R7; G protein-coupled receptor; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; RDC-1; unnamed protein product
Gene Aliases: ACKR3; AW541270; CMKOR1; CXC-R7; CXCR-7; CXCR7; GPR159; RDC-1; RDC1
UniProt ID: (Human) P25106, (Mouse) P56485
Entrez Gene ID: (Human) 57007, (Mouse) 12778
angiogenesis
vasculogenesis
positive regulation of defense response to virus by host
chemotaxis
cell adhesion
signal transduction
G-protein coupled receptor signaling pathway
multicellular organism development
receptor internalization
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
immune response
positive regulation of cytosolic calcium ion concentration
negative regulation of cell proliferation
calcium-mediated signaling
oculomotor nerve development
cell chemotaxis
positive regulation of mesenchymal stem cell migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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