Search
Proteintech
Hexokinase 1 Monoclonal Antibody (2B4F9)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
68419-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
2B4F9
Immunogen
Hexokinase 1 fusion protein Ag8015
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: SDFLDYMGIK GPRMPLGFTF SFPCQQTSLD AGILITWTKG FKATDCVGHD VVTLLRDAIK RREEFDLDVV AVVNDTVGTM MTCAYEEPTC EVGLIVGTGS NACYMEEMKN VEMVEGDQGQ MCINMEWGAF GDNGCLDDIR THYDRLVDEY SLNAGKQRYE KMISGMYLGE IVRNILIDFT KKGFLFRGQI SETLKTRGIF ETKFLSQIES DRLALLQVRA ILQQLGLNST CDDSILVKTV CGVVSRRAAQ LCGAGMAAVV DKIRENRGLD RLNVTVGVDG TLYKLHPHFS RIMHQTVKEL SPKCNVSFLL SEDGSGKGAA LITAVGVRLR TEASS
Target Information
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Brain form hexokinase; downeast anemia; glycolytic enzyme; hexokinase IR; Hexokinase type I; Hexokinase, tumor isozyme; Hexokinase-1; Hexokinase-A; HK I; HK1-td; Neuropathy, hereditary motor and sensory, Russe type; unnamed protein product
Gene Aliases: BB404130; CNSHA5; dea; HEXOKIN; hexokinase; HK; Hk-1; HK1; Hk1-s; HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1; mHk1-s; NEDVIBA; NMSR; RP79
UniProt ID: (Human) P19367, (Rat) P05708, (Mouse) P17710
Entrez Gene ID: (Pig) 100152344, (Human) 3098, (Rat) 25058, (Mouse) 15275
nucleotide binding
catalytic activity
glucokinase activity
hexokinase activity
protein binding
ATP binding
glucose binding
fructokinase activity
kinase activity
transferase activity
phosphotransferase activity, alcohol group as acceptor
mannokinase activity
peptidoglycan binding
glucosamine kinase activity
protein kinase activity
ATPase activity
protein complex binding
protein homodimerization activity
kinase
cellular glucose homeostasis
immune system process
positive regulation of cytokine production involved in immune response
carbohydrate metabolic process
fructose 6-phosphate metabolic process
glucose metabolic process
mannose metabolic process
glycolytic process
inflammatory response
GDP-mannose biosynthetic process
hexose metabolic process
organophosphate metabolic process
positive regulation of interleukin-1 beta production
innate immune response
carbohydrate phosphorylation
glucose 6-phosphate metabolic process
canonical glycolysis
GDP-mannose biosynthetic process from mannose
establishment of protein localization to mitochondrion
maintenance of protein location in mitochondrion
carbohydrate derivative metabolic process
response to ischemia
protein phosphorylation
regulation of anion channel activity
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
peptidyl-tyrosine phosphorylation
negative regulation of apoptotic process
protein autophosphorylation
metabolic process
phosphorylation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support