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Invitrogen
Eotaxin Recombinant Rabbit Monoclonal Antibody (9H3L1)
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FIGURE: 1 / 1
Eotaxin Antibody (702314) in ELISA
Indirect ELISA analysis of Anti-CCL11 Recombinant Rabbit Monoclonal Antibody (Product # 702314) was performed by coating recombinant human CCL11 protein standard at concentrations ranging from 0.24 ng/mL to 250 ng/mL onto a plate. The coated protein was bound by Anti-CCL11 Recombinant Rabbit Monoclonal Antibody at 1 µg/mL and was detected using Goat anti-Rabbit IgG (H+L) secondary antibody, HRP-conjugate (Product # G-21234, 1:5000 dilution). The plate was developed using stabilized chromogen solution, TMB+H2O2 (Product # SB01). The plate w... View More
Product Details
702314
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
9H3L1
Immunogen
Protein corresponding to Human CCL11 (aa 24-97)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
Product Specific Information
This antibody is predicted to react with Monkey, rabbit and horse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-C motif chemokine 11; CCL11; chemokine (C-C motif) ligand 11; Eosinophil Chemotactic Factor; Eosinophil chemotactic protein; Eotaxin; Eotaxin 1; eotaxin-1; Eotaxin1; MGC22554; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); Small-inducible cytokine A11
Gene Aliases: CCL11; SCYA11
UniProt ID: (Human) P51671
Entrez Gene ID: (Human) 6356
positive regulation of endothelial cell proliferation
chronic inflammatory response
mast cell chemotaxis
protein phosphorylation
cellular calcium ion homeostasis
chemotaxis
inflammatory response
immune response
cytoskeleton organization
actin filament organization
cell adhesion
signal transduction
learning or memory
regulation of cell shape
response to radiation
response to virus
positive regulation of cell migration
positive regulation of actin filament polymerization
killing of cells of other organism
response to interleukin-13
positive regulation of angiogenesis
eosinophil chemotaxis
negative regulation of neurogenesis
branching involved in mammary gland duct morphogenesis
mammary duct terminal end bud growth
antimicrobial humoral immune response mediated by antimicrobial peptide
chemokine-mediated signaling pathway
ERK1 and ERK2 cascade
response to interleukin-4
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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