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Invitrogen
Transthyretin Recombinant Rabbit Monoclonal Antibody (24H23L8)
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FIGURE: 1 / 4
Transthyretin Antibody (703278) in ICC/IF
For immunocytochemistry analysis, HepG2 cells were fixed and permeabilized for detection of endogenous Transthyretin using Anti-Transthyretin Recombinant Rabbit Monoclonal Antibody (Product # 703278) at a 1:100 dilution and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) at a 1:2000 dilution. Panel a) shows representative cells t... View More
Product Details
703278
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
24H23L8
Immunogen
Protein corresponding to human Transthyretin [aa21-aa147]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
Product Specific Information
This antibody is predicted to react with Mouse, Rat, Bovine.
Target Information
Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Amyloidosis I; ATTR; epididymis luminal protein 111; pre-albumin; Prealbumin; prealbumin, amyloidosis type I; TBPA; thyroxine-binding prealbumin; Transthyretin; TTR; unnamed protein product
Gene Aliases: ATTR; CTS; CTS1; HEL111; HsT2651; PALB; TBPA; TTN; TTR
UniProt ID: (Human) P02766
Entrez Gene ID: (Human) 7276
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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