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          • Primary Antibodies ›
          • Pan-cadherin Antibodies

          Invitrogen

          Pan-cadherin Polyclonal Antibody

          2 Published Figures
          17 References
          View all (16) Pan-cadherin antibodies

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          Cite Pan-cadherin Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (8)
          • Published Figures (2)
          Pan-cadherin Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          Pan-cadherin Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 10

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          Pan-cadherin Antibody (71-7100) in ICC/IF

          Immunofluorescence analysis of Pan-Cadherin was performed using 90% confluent log phase Caco-2 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Cadherin pan Rabbit Polyclonal Antibody (Product # 71-7100) at 2 µg/mL in 0.1% BSA and incubated for 3 hours... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          Pan-cadherin Antibody in Immunocytochemistry (ICC/IF)
          Pan-cadherin Antibody in Immunocytochemistry (ICC/IF)
          Pan-cadherin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Pan-cadherin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Pan-cadherin Antibody in Western Blot (WB)
          Pan-cadherin Antibody in Western Blot (WB)
          Pan-cadherin Antibody in Western Blot (WB)
          Pan-cadherin Antibody in Western Blot (WB)
          Pan-cadherin Antibody in Western Blot (WB)
          Pan-cadherin Antibody in Western Blot (WB)
          Pan-cadherin Polyclonal Antibody

          Product Details

          71-7100

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-2 µg/mL
          View 10 publications 10 publications

          Immunohistochemistry (IHC)

          -
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          2-3 µg/mL
          View 2 publications 2 publications

          ELISA (ELISA)

          Assay-dependent
          -

          Miscellaneous PubMed (Misc)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Dog, Chicken, Human, Mouse, Non-human primate, Rat, Xenopus

          Published species

          Bovine, Dog, Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide derived from the carboxy-terminus of the chicken N-cadherin protein.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.25 mg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.4

          Contains

          0.1% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2533992

          Product Specific Information

          This peptide antibody is broadly cross-reactive with all members of the cadherin family of proteins including N-cadherin, E-cadherin, P-cadherin, and R-cadherin. The antibody also displays broad species cross-reactivity including human, bovine, mouse, rat, chicken, amphibian, as well as other species. Rabbit anti-pan-Cadherin is useful as both a ubiquitous cadherin probe as well as a marker for adherens junctions.

          71-7100 was used successfully in the immunofluorescence analysis of pan cadherin in MDCK cells.

          Target Information

          Pan Cadherin including CDH1, CDH2, CDH3, CDH4 protein belong to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: ARC-1; cadherin 1, E-cadherin (epithelial); cadherin 1, type 1, E-cadherin (epithelial); cadherin 15, M-cadherin (myotubule); cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal); cadherin 3, type 1, P-cadherin (placental); cadherin 4 type 1 R-cadherin (retinal); cadherin 4, type 1, preproprotein; cadherin 4, type 1, R-cadherin (retinal); cadherin e; Cadherin-1; Cadherin-2; Cadherin-3; Cadherin-4; cadherin-E; Cadherin-N; calcium-dependent adhesion protein, epithelial; calcium-dependent adhesion protein, neuronal; calcium-dependent adhesion protein, placental; CAM 120/80; CD324; CD325; CDH1; CDw325; CDw325 antigen; cell-CAM 120/80; E-cadherin; E-cadherin 1; epididymis secretory sperm binding protein; Epithelial cadherin; L-CAM; Liver cell adhesion molecule; liver cell adhesion protein; Maternally-expressed neural cadherin; N-cadherin; N-cadherin 1; Neural cadherin; neural calcium-dependent cell adhesion molecule; Neural-cadherin; P-cadherin; Pan Cadherin; Placental cadherin; Placental-cadherin; R-CAD; R-cadherin; retina cadherin; Retinal cadherin; RPE-specific cadherin; unnamed protein product; Uvomorulin; XmN-cadherin; xTCAD-1

          View more View less

          Gene Aliases: AA960649; ACOGS; ADHD8; AI385538; Arc-1; ARVD14; AW120700; BCDS1; CAD4; Cadherin-1; cadherin-2; cadherin-4; Cadp; CD324; CD325; CDH1; CDH2; CDH3; CDH4; Cdh4l; CDHE; CDHN; CDHP; CDw325; E-cad; ECAD; HJMD; K-CAM; L-CAM; LCAM; N-cadherin; NCAD; P-cadherin; PCAD; R-CAD; R-Cadh; R-cadherin; RCAD; Um; UVO; Uvomorulin; XELAEV_18024918mg; XELAEV_18046239mg

          View more View less

          UniProt ID: (Human) P12830, (Chicken) P08641, (Dog) F1PAA9, (Chicken) P10288, (Human) P19022, (Human) P22223, (Chicken) P24503, (Human) P55283, (Mouse) P09803, (Rat) Q9R0T4, (Mouse) P15116, (Rat) Q9Z1Y3, (Mouse) P10287, (Mouse) P39038, (Xenopus) P79883, (Xenopus) P30944

          View more View less

          Entrez Gene ID: (Human) 999, (Chicken) 415860, (Dog) 442858, (Dog) 480169, (Chicken) 414745, (Human) 1000, (Dog) 611010, (Human) 1001, (Chicken) 414845, (Chicken) 419222, (Human) 1002, (Dog) 100685099, (Mouse) 12550, (Rat) 83502, (Mouse) 12558, (Rat) 83501, (Rat) 116777, (Mouse) 12560, (Mouse) 12561, (Rat) 114588, (Xenopus) 108702627, (Xenopus) 100337618

          View more View less

          Function(s)
          calcium ion binding protein binding beta-catenin binding ankyrin binding GTPase activating protein binding identical protein binding gamma-catenin binding cadherin binding metal ion binding cell adhesion molecule binding protein binding involved in cell-cell adhesion protein tyrosine kinase binding protein kinase binding protein phosphatase binding alpha-catenin binding extracellular matrix binding RNA binding enzyme binding glycoprotein binding protein domain specific binding protein complex binding nitric-oxide synthase binding molecular_function cadherin
          Process(es)
          cell morphogenesis desmosome assembly cell-cell junction assembly cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules synapse assembly response to xenobiotic stimulus response to toxic substance regulation of gene expression calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell migration pituitary gland development negative regulation of cell-cell adhesion negative regulation of cell migration negative regulation of axon extension neuron projection development cell junction assembly adherens junction organization positive regulation of protein import into nucleus cell-cell adhesion mediated by cadherin positive regulation of transcription, DNA-templated regulation of transport cellular response to lithium ion response to heparin cellular response to indole-3-methanol protein localization to plasma membrane cell-cell adhesion regulation of protein catabolic process at postsynapse, modulating synaptic transmission response to Gram-positive bacterium positive regulation of cellular protein localization cell-cell adhesion via plasma-membrane adhesion molecules cartilage condensation neural tube formation heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules brain development glial cell differentiation neural crest cell delamination positive regulation of MAPK cascade blood vessel morphogenesis brain morphogenesis homeostasis of number of cells regulation of axonogenesis striated muscle cell differentiation regulation of synaptic transmission, glutamatergic radial glial cell differentiation limb development neuroepithelial cell differentiation trigeminal ganglion formation trigeminal ganglion structural organization regulation of oligodendrocyte progenitor proliferation negative regulation of canonical Wnt signaling pathway neuroligin clustering involved in postsynaptic membrane assembly neuronal stem cell population maintenance cell aggregation regulation of postsynaptic density protein 95 clustering positive regulation of synaptic vesicle clustering type B pancreatic cell development neural crest cell development telencephalon development cerebral cortex development detection of muscle stretch mesenchymal cell migration synaptic vesicle clustering retina homeostasis visual perception positive regulation of gene expression positive regulation of keratinocyte proliferation hair cycle process negative regulation of transforming growth factor beta receptor signaling pathway keratinization positive regulation of monophenol monooxygenase activity positive regulation of insulin-like growth factor receptor signaling pathway positive regulation of melanin biosynthetic process negative regulation of catagen positive regulation of canonical Wnt signaling pathway positive regulation of melanosome transport axon guidance positive regulation of axon extension axon extension in utero embryonic development trophectodermal cell differentiation epithelial cell morphogenesis sensory perception of sound single organismal cell-cell adhesion protein metabolic process regulation of protein localization regulation of water loss via skin positive regulation of transcription factor import into nucleus regulation of cysteine-type endopeptidase activity involved in apoptotic process regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation protein homooligomerization intestinal epithelial cell development salivary gland cavitation regulation of branching involved in salivary gland morphogenesis bicellular tight junction assembly cellular response to amino acid stimulus establishment of protein localization to plasma membrane cochlea development regulation of protein localization to cell surface regulation of neuron migration response to organic substance response to drug regulation of signal transduction regulation of myelination regulation of Rho protein signal transduction protein heterooligomerization negative regulation of transforming growth factor beta2 production wound healing canonical Wnt signaling pathway regulation of hair cycle by canonical Wnt signaling pathway
          It has to be done as per old AB suggested Products section.

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