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Invitrogen
Annexin A6 Polyclonal Antibody
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FIGURE: 1 / 4
Annexin A6 Antibody (720161) in ICC/IF
Immunofluorescence was performed on fixed and permeabilized C2C12 cells for detection of Annexin A6 using Anti-Annexin A6 Rabbit Polyclonal Antibody (Product # 720161, 1 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of Annex... View More
Product Details
720161
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ANXA6 (aa 500-673)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 30% glycerol, 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.
This antibody is predicted to react with Monkey, Rat, Mouse and Rabbit.
Target Information
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 67 kDa calelectrin; Annexin A6; Annexin VI; annexin VI (p68); annexin VI, p68; Annexin-6; calcium-binding protein p68; calelectrin; calphobindin II; Calphobindin-II; Chromobindin-20; CPB-II; Lipocortin VI; p68; p70; Protein III; testis secretory sperm-binding protein Li 198a; unnamed protein product
Gene Aliases: ANX6; ANXA6; AnxVI; AW107198; Cabm; Camb; CBP68; CPB-II; p68; p70
UniProt ID: (Human) P08133, (Mouse) P14824
Entrez Gene ID: (Human) 309, (Mouse) 11749
phosphatidylserine binding
calcium ion binding
protein binding
GTP binding
calcium-dependent phospholipid binding
lipid binding
ligand-gated ion channel activity
cholesterol binding
identical protein binding
calcium-dependent protein binding
protein complex binding
protein homodimerization activity
calcium-binding protein
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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