Search
Bethyl Laboratories
SRC1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
A300-343A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residues 600 and 650 of Human Nuclear Receptor Coactivator 1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
Target Information
Clone 1135 recognizes SRC-1, steroid-receptor coactivator-1. SRC-1 is a member of a gene family that functions in the full transcriptional activation of the steroid hormone receptor superfamily and contains intrinsic histone acetyltransferase activity. SRC-1 has a molecular weight of 160 kDa and has a basic helix-loop-helix (bHLH)-PAS domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ASV; bHLHe74; c-SRC; Class E basic helix-loop-helix protein 74; Hin-2; Hin-2 protein; mNRC-1; NCoA-1; Nuclear receptor coactivator 1; Nuclear receptor coactivator protein 1; p60-Src; Protein Hin-2; Renal carcinoma antigen NY-REN-52; RIP160; SRC-1; SRC-1 (-Q); SRC-a/NCoA-1; Steroid receptor coactivator 1; steroid receptor coactivator-1; unnamed protein product
Gene Aliases: bHLHe42; BHLHE74; F-SRC-1; KAT13A; NCOA1; RIP160; SRC-1; SRC1
UniProt ID: (Human) Q15788, (Mouse) P70365
Entrez Gene ID: (Human) 8648, (Mouse) 17977
RNA polymerase II regulatory region sequence-specific DNA binding
DNA binding
chromatin binding
transcription coactivator activity
histone acetyltransferase activity
protein binding
transferase activity
transferase activity, transferring acyl groups
ligand-dependent nuclear receptor binding
estrogen receptor binding
retinoic acid receptor binding
macromolecular complex binding
retinoid X receptor binding
protein dimerization activity
peptide-lysine-N-acetyltransferase activity
RNA polymerase II regulatory region DNA binding
signal transducer activity
transcription factor binding
enzyme binding
ligand-dependent nuclear receptor transcription coactivator activity
protein complex binding
progesterone receptor binding
nuclear hormone receptor binding
protein N-terminus binding
histone modifying enzyme
positive regulation of transcription from RNA polymerase II promoter by galactose
regulation of thyroid hormone mediated signaling pathway
chromatin remodeling
regulation of transcription, DNA-templated
lactation
male gonad development
response to hormone
cerebellum development
hippocampus development
hypothalamus development
cerebral cortex development
intracellular estrogen receptor signaling pathway
response to estradiol
response to retinoic acid
response to progesterone
cellular response to hormone stimulus
peroxisome proliferator activated receptor signaling pathway
mRNA transcription from RNA polymerase II promoter
positive regulation of apoptotic process
estrous cycle
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of female receptivity
positive regulation of transcription from RNA polymerase II promoter
progesterone receptor signaling pathway
male mating behavior
labyrinthine layer morphogenesis
regulation of cellular response to insulin stimulus
cellular response to Thyroglobulin triiodothyronine
positive regulation of adipose tissue development
transcription, DNA-templated
signal transduction
histone H4 acetylation
regulation of nucleic acid-templated transcription
regulation of cellular response to drug
regulation of RNA biosynthetic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support