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Bethyl Laboratories
SART3/TIP110 Polyclonal Antibody
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FIGURE: 1 / 2
SART3/TIP110 Antibody (A301-521A) in IHC (P)
Detection of human SART3/TIP110 by immunohistochemistry and immunofluorescence. Sample: FFPE sections of human ovarian carcinoma (left) and colon carcinoma (right). Antibody: Affinity purified rabbit anti-SART3/TIP110 (Product # A301-521A) (Lot 1) used at a dilution of 1:200 (1 µg/mL) and 1:400 (0.5 µg/mL). Detection: DAB. and Red-fluorescent goat anti-rabbit IgG-heavy and light chain, cross-adsorbed Antibo... View More
Product Details
A301-521A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 600 and 650 of Human squamous cell carcinoma antigen recognized by T-cells 3 (Tat-interacting protein of 110 kDa).
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HIV-1 Tat-interacting protein of 110kDa; hSART-3; KIAA0156; MGC138188; p110 nuclear RNA-binding protein; pretruncated isoform; PRP24 homolog; SART-3; Spliceosome associated factor 3, U4/U6 recycling protein; squamous cell carcinoma antigen recognized by T cells 3; Squamous cell carcinoma antigen recognized by T-cells 3; Tat-interacting protein of 110 kDa; Tip110; unnamed protein product
Gene Aliases: DSAP1; KIAA0156; P100; p110; p110(nrb); RP11-13G14; SART3; TIP110
UniProt ID: (Human) Q15020
Entrez Gene ID: (Human) 9733
spliceosomal tri-snRNP complex assembly
spliceosomal snRNP assembly
mRNA splicing, via spliceosome
cell morphogenesis
nucleosome assembly
RNA processing
mRNA processing
RNA splicing
regulation of gene expression
homeostasis of number of cells
regulation of RNA metabolic process
hematopoietic stem cell proliferation
transcription elongation-coupled chromatin remodeling
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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