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Bethyl Laboratories
MCSP Polyclonal Antibody
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FIGURE: 1 / 1
MCSP Antibody (A302-121A) in WB
Detection of human MCSP by western blot and immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-MCSP antibody (Product # A302-121A) used for WB at 0.04 µg/mL (A) and 0.4 µg/mL (B) and used for IP at 10 µg/mg lysate. MCSP was also immunoprecipitated by rabbit anti-MCSP antibody A302-122A, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds (B).
Product Details
A302-121A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 575 and 625 of human melanoma-associated chondroitin sulfate proteoglycan (chondroitin sulfate proteoglycan 4).
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell surface proteoglycan; Chondroitin sulfate proteoglycan 4; chondroitin sulfate proteoglycan 4 (melanoma-associated); Chondroitin sulfate proteoglycan NG2; HMW MAA; MEL CSPG; Melanoma chondroitin sulfate proteoglycan; Melanoma-associated chondroitin sulfate proteoglycan
Gene Aliases: CSPG4; CSPG4A; HMW-MAA; MCSP; MCSPG; MEL-CSPG; MSK16; NG2
UniProt ID: (Human) Q6UVK1
Entrez Gene ID: (Human) 1464
angiogenesis
substrate-dependent cell migration
signal transduction
glial cell migration
cell differentiation
intracellular signal transduction
positive regulation of MAPK cascade
platelet-derived growth factor receptor signaling pathway
tissue remodeling
positive regulation of peptidyl-tyrosine phosphorylation
ruffle assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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