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Bethyl Laboratories
Hexokinase 1 Polyclonal Antibody
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FIGURE: 1 / 1
Hexokinase 1 Antibody (A304-252A) in WB
Detection of human and mouse Hexokinase 1 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells. Antibodies: Affinity purified rabbit anti-Hexokinase 1 antibody (Product # A304-252A) (lot A304-252A-1) used for WB at 0.4 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A304-252A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 325 to 375 of human Hexokinase 1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain form hexokinase; downeast anemia; glycolytic enzyme; hexokinase IR; Hexokinase type I; Hexokinase, tumor isozyme; Hexokinase-1; Hexokinase-A; HK I; HK1-td; Neuropathy, hereditary motor and sensory, Russe type; unnamed protein product
Gene Aliases: BB404130; CNSHA5; dea; hexokinase; HK; Hk-1; HK1; Hk1-s; HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1; mHk1-s; NEDVIBA; NMSR; RP79
UniProt ID: (Human) P19367, (Mouse) P17710
Entrez Gene ID: (Human) 3098, (Mouse) 15275
nucleotide binding
catalytic activity
glucokinase activity
hexokinase activity
protein binding
ATP binding
glucose binding
fructokinase activity
kinase activity
transferase activity
phosphotransferase activity, alcohol group as acceptor
mannokinase activity
peptidoglycan binding
glucosamine kinase activity
protein kinase activity
protein complex binding
protein homodimerization activity
kinase
cellular glucose homeostasis
immune system process
positive regulation of cytokine production involved in immune response
carbohydrate metabolic process
fructose 6-phosphate metabolic process
glucose metabolic process
mannose metabolic process
glycolytic process
inflammatory response
GDP-mannose biosynthetic process
hexose metabolic process
organophosphate metabolic process
positive regulation of interleukin-1 beta production
innate immune response
carbohydrate phosphorylation
glucose 6-phosphate metabolic process
canonical glycolysis
GDP-mannose biosynthetic process from mannose
establishment of protein localization to mitochondrion
maintenance of protein location in mitochondrion
carbohydrate derivative metabolic process
response to ischemia
protein phosphorylation
metabolic process
regulation of anion channel activity
phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
peptidyl-tyrosine phosphorylation
negative regulation of apoptotic process
protein autophosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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