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RNF131 Polyclonal Antibody
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Product Details
BS-9290R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human PJA2/RNF131, amino acids 420-470.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA-mediated long-term memory processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase Praja-2; E3 ubiquitin-protein ligase Praja2; KIAA0438; neurodegeneration associated protein 1; praja 2, RING-H2 motif containing; praja ring finger 2, E3 ubiquitin protein ligase; praja-2; Praja2; protein carrying the RING-H2 sequence motif; RING finger protein 131; RING-type E3 ubiquitin transferase Praja-2; unnamed protein product
Gene Aliases: AI447901; AL022700; KIAA0438; mKIAA0438; Neurodap1; PJA2; praja2; RNF131
UniProt ID: (Human) O43164, (Mouse) Q80U04, (Rat) Q63364
Entrez Gene ID: (Human) 9867, (Mouse) 224938, (Rat) 192256
ubiquitin-protein transferase activity
protein binding
zinc ion binding
transferase activity
protein kinase A catalytic subunit binding
protein kinase A regulatory subunit binding
metal ion binding
ubiquitin protein ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
inflammatory response
long-term memory
regulation of protein kinase A signaling
protein ubiquitination
positive regulation of toll-like receptor 2 signaling pathway
regulation of macrophage activation
proteasome-mediated ubiquitin-dependent protein catabolic process
innate immune response
positive regulation of JNK cascade
positive regulation of p38MAPK cascade
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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