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OriGene
DLD Monoclonal Antibody (OTI4D5), TrueMAB™
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Product Details
CF503423
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4D5
Immunogen
Full length human recombinant protein of human DLD produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: diaphorase; Dihydrolipoamide dehydrogenase; dihydrolipoamide dehydrogenase precursor; Dihydrolipoyl dehydrogenase, mitochondrial; E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex; epididymis secretory sperm binding protein; Glycine cleavage system L protein; glycine cleavage system protein L; lipoamide dehydrogenase; lipoamide dehydrogenase precursor old gene name 'LAD'; lipoamide reductase; lipoyl dehydrogenase; OTTHUMP00000206744; OTTHUMP00000206746; OTTHUMP00000206748; OTTHUMP00000206749; PH; PHE 3; pyruvate dehydrogenase complex subunit E3, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex, glycine cleavage system protein L; unnamed protein product
Gene Aliases: DLD; DLDD; DLDH; E3; GCSL; LAD; OGDC-E3; PHE3
UniProt ID: (Human) P09622
Entrez Gene ID: (Human) 1738
acetyl-CoA biosynthetic process from pyruvate
pyruvate metabolic process
2-oxoglutarate metabolic process
mitochondrial electron transport, NADH to ubiquinone
proteolysis
gastrulation
branched-chain amino acid catabolic process
regulation of membrane potential
sperm capacitation
2-oxoglutarate decarboxylation to succinyl-CoA
branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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