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Proteintech
HuR Monoclonal Antibody (1A11H2), CoraLite® 594
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Product Details
CL594-66549
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1A11H2
Immunogen
Full length HuR protein.
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Target Information
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); ELAV like 1; Elav-like generic protein; ELAV-like protein 1; embryonic lethal, abnormal vision, drosophila, homolog-like 1; Hu antigen R; HU-antigen A; Hu-antigen R; Human antigen R; HuR; MelG; unnamed protein product
Gene Aliases: 2410055N02Rik; ELAV1; ELAVL1; Elra; Hua; HUR; MelG; W91709
UniProt ID: (Human) Q15717, (Mouse) P70372, (Rat) B5DF91
Entrez Gene ID: (Human) 1994, (Mouse) 15568, (Rat) 363854
nucleic acid binding
RNA binding
double-stranded RNA binding
mRNA binding
mRNA 3'-UTR binding
protein binding
protein kinase binding
miRNA binding
mRNA 3'-UTR AU-rich region binding
protein homodimerization activity
lncRNA binding
nucleotide binding
AU-rich element binding
poly(A) RNA binding
translation initiation factor
lncRNA-mediated post-transcriptional gene silencing
protein import into nucleus
cell proliferation
response to glucose
positive regulation of autophagy
posttranscriptional gene silencing
positive regulation of superoxide anion generation
regulation of mRNA stability
positive regulation of translation
positive regulation of autophagosome size
mRNA stabilization
protein homooligomerization
negative regulation of gene silencing by miRNA
mRNA destabilization
3'-UTR-mediated mRNA stabilization
regulation of stem cell population maintenance
regulation of translation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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