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Invitrogen
TBP Monoclonal Antibody (1TBP18)
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FIGURE: 1 / 4
TBP Antibody (MA1-189) in ICC/IF
Immunofluorescent analysis of TATA binding protein (green) in U2OS cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.1% Triton X-100 in PBS for 15 minutes, and blocked with 3% BSA in PBS (Product # 37525) for 30 minutes at room temperature. Cells were stained with a TBP monoclonal antibody (Product # MA1-189) at a dilution of 10 µg/mL in staining buffer for 1 hour at room temperature, and then incubated with a Goat anti-Mouse IgG Superclonal Secondary Antibody, Alexa Fluor 488 conjugate (Product # A2... View More
Product Details
MA1-189
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Non-human primate,
Rat
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1TBP18
Immunogen
N-terminal domain of the human TATA-binding protein (TBP)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 30% glycerol, 1mg/mL BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA1-189 detects TATA-Binding Protein from human, mouse, and rat, canine, and non-human primate samples. TBP (human) has an approximate molecular weight of 38kDa, while other species' isoforms can range from 35-36kDa.
MA1-189 has been successfully used in Western blot and immunofluorescence and flow cytometry applications.
The MA1-189 immunogen is the N-terminal domain of the human TATA-binding protein (TBP).
Target Information
RICH1 is a GTPase-activating protein (GAP). GAPs stimulate the intrinsic GTP hydrolysis of small G proteins, such as RHOA, RAC1, and CDC42.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MGC117320; MGC126054; MGC126055; RP1-191N21.3; TATA binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-binding protein; TATA-box binding protein N-terminal domain; TATA-box factor; tata-box-binding; TATA-box-binding protein; TBP; TFIID; TFIID core protein; Transcription initiation factor TFIID TBP subunit; unnamed protein product
Gene Aliases: GTF2D; GTF2D1; HDL4; SCA17; TBP; TBP1; TF2D; TFIID
UniProt ID: (Human) P20226, (Mouse) P29037
Entrez Gene ID: (Human) 6908, (Dog) 611193, (Mouse) 21374, (Rat) 117526
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcription factor activity, core RNA polymerase III binding
core promoter sequence-specific DNA binding
RNA polymerase II general transcription initiation factor binding
TFIIB-class transcription factor binding
RNA polymerase I CORE element sequence-specific DNA binding
DNA binding
protein binding
obsolete general RNA polymerase II transcription factor activity
aryl hydrocarbon receptor binding
enzyme binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
DNA-binding transcription factor binding
RNA polymerase II repressing transcription factor binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
transcription regulatory region DNA binding
repressing transcription factor binding
general transcription factor
RNA polymerase I preinitiation complex assembly
DNA-templated transcription, initiation
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription from RNA polymerase III promoter
spermatogenesis
mRNA transcription from RNA polymerase II promoter
positive regulation of transcription, DNA-templated
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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