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Invitrogen
SLC5A7 Monoclonal Antibody (62-2E8)
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Product Details
MA1-46409
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Published species
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
62-2E8
Immunogen
Recombinant fusion protein from the C-terminal portion of the human CHT1 protein.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
PBS with 50% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In Western blot a band can be seen at ~65 kDa representing CHT and a band can also be seen at ~45 kDa after deglycosylation with PNGase F.
Suggested positive control: antigen standard for SLC5A7 (transient overexpression lysate), rat striatum protein.
Target Information
Acetylcholine functions as a neurotransmitter in both the central and peripheral nervous systems of all vertebates, and is the principle neurotransmitter used at the neuromuscular junction. Presynaptic synthesis of acetylcholine requires a steady supply of choline, which is acquired by a plasma membrane high affinity choline transporter (CHT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CHT; hCHT; hCHT1; Hemicholinium-3-sensitive choline transporter; High affinity choline transporter 1; high affinity choline transporter; hemicholinium-3-sensitive choline transporter; MGC126299; MGC126300; Motor neuronopathy, distal hereditary, type VIIA; Motor neuronopathy, distal hereditary, with vocal cord paresis; rCHT1; solute carrier family 5 (choline transporter), member 7; solute carrier family 5 (sodium/choline cotransporter), member 7; Solute carrier family 5 member 7; solute carrier family 5, member 7; unnamed protein product
Gene Aliases: CHT; CHT1; CMS20; DHMNVP; hCHT1; HMN7A; HMND7; SLC5A7
UniProt ID: (Human) Q9GZV3, (Mouse) Q8BGY9, (Rat) Q9JMD7
Entrez Gene ID: (Human) 60482, (Mouse) 63993, (Rat) 85426
in utero embryonic development
ion transport
sodium ion transport
neurotransmitter transport
synaptic transmission, cholinergic
neuromuscular synaptic transmission
acetylcholine biosynthetic process
choline transport
transmembrane transport
transport
organic cation transport
sodium ion transmembrane transport
neurotransmitter biosynthetic process
ammonium transmembrane transport
cation transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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