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Invitrogen
HP1 gamma Monoclonal Antibody (2MOD-1G6)
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FIGURE: 1 / 7
HP1 gamma Antibody (MA3-054) in ICC/IF
Immunofluorescent analysis of HP1-gamma (green) in HeLa cells. The cells were fixed with formalin for 15 minutes, permeabilized with 1X Permeablilization buffer (Product # 8408400) for 15 minutes, and blocked with 1% Blocker BSA (Product # 37525) for 15 minutes at room temperature. Cells were stained with HP1-gamma monoclonal antibody (Product # MA3-054) at a dilution of 1:250 in blocking buffer for one hou... View More
Product Details
MA3-054
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2MOD-1G6
Immunogen
Recombinant HP1-gamma mouse
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA3-054 detects HP1-gamma in human, mouse and rat samples.
MA3-054 has been succesfully used in western blot, ELISA, immunofluorescence and ChIP applications.
Immunogen is a HP1-gamma recombinant mouse
Target Information
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: chromobox homolog 3; chromobox homolog 3 (HP1 gamma homolog, Drosophila); Chromobox protein homolog 3; HECH; heterochromatin protein 1 gamma; Heterochromatin protein 1 homolog gamma; heterochromatin protein HP1 gamma; heterochromatin-like protein 1; HGNC:1553; HP1 gamma; HP1 gamma homolog; HPy; Modifier 2 protein; OTTHUMP00000202463
Gene Aliases: CBX3; HECH; HP1-GAMMA; HP1g; HP1gamma; HP1Hs-gamma; M32
UniProt ID: (Human) Q13185
Entrez Gene ID: (Human) 11335, (Mouse) 12417, (Rat) 297093
chromatin organization
chromatin remodeling
cellular response to DNA damage stimulus
heterochromatin assembly
negative regulation of transcription, DNA-templated
rhythmic process
cellular response to dexamethasone stimulus
transcription, DNA-templated
regulation of transcription, DNA-templated
chromatin modification
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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