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Invitrogen
Cytokeratin 19 Monoclonal Antibody (RCK108)
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FIGURE: 1 / 4
Cytokeratin 19 Antibody (MA5-12613) in ICC/IF
Immunofluorescent analysis of Cytokeratin 19 was performed using 90% confluent log phase MCF-7 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Cytokeratin 19 (RCK108) Mouse Monoclonal Antibody (Product # MA5-12613) at 1:250 dilution in 0.1% BSA and in... View More
Product Details
MA5-12613
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
RCK108
Immunogen
Cytoskeleton preparation of T24 cells
Conjugate
Form
Liquid
Storage conditions
4°C
Shipping conditions
Wet ice
RRID
Product Specific Information
MA5-12613 targets Cytokeratin 19 in IHC (P) and WB applications and shows reactivity with Human samples.
The MA5-12613 immunogen is cytoskeleton preparation of T24 cells.
Target Information
Cytokeratin 19 is part of a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight from 40-68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. For example, cytokeratin 19 is not expressed in hepatocytes, therefore, it is useful in the identification of liver metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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