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Invitrogen
CD155 Monoclonal Antibody (D171)
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FIGURE: 1 / 6
CD155 Antibody (MA5-13493) in ICC/IF
Immunofluorescent analysis of CD155 (green) showing staining in the membrane of U-87 MG cells (right) compared to a negative control without primary antibody (left). Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with a CD155 monoclonal antibody (Product # MA5-13493) in 3% BSA-PBS at a dilution of 1:20 and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight-conju... View More
Product Details
MA5-13493
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
D171
Immunogen
HeLa cells
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-13493 targets CD155 in Western blot, FACS and ICC/IF applications and shows reactivity with Human, Mouse and Non-human primate samples.
The MA5-13493 immunogen is HeLa cells.
Target Information
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD155; FLJ25946; NECL-5; nectin-like 5; Nectin-like protein 5; Poliovirus receptor; sCD112; soluble CD112; tumor-associated antigen 1; unnamed protein product
Gene Aliases: 3830421F03Rik; CD155; D7Ertd458e; HVED; mE4; Necl-5; NECL5; PVR; PVS; Taa1; TAGE4
UniProt ID: (Human) P15151
Entrez Gene ID: (Human) 5817, (Mouse) 52118
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
signal transduction
natural killer cell mediated cytotoxicity
susceptibility to natural killer cell mediated cytotoxicity
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
viral entry into host cell
susceptibility to T cell mediated cytotoxicity
single organismal cell-cell adhesion
cell migration
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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