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Invitrogen
HK1 Monoclonal Antibody (7A7)
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Product Details
MA5-15675
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
7A7
Immunogen
Purified recombinant fragment of human HK1 expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-15675 targets HK1 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human, mouse, and Rat samples.
The MA5-15675 immunogen is purified recombinant fragment of human HK1 expressed in E. Coli.
MA5-15675 detects HK1 which has a predicted molecular weight of approximately 102kDa.
Target Information
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Brain form hexokinase; downeast anemia; glycolytic enzyme; hexokinase IR; Hexokinase type I; Hexokinase, tumor isozyme; Hexokinase-1; Hexokinase-A; HK I; HK1-td; Neuropathy, hereditary motor and sensory, Russe type; unnamed protein product
Gene Aliases: BB404130; CNSHA5; dea; HEXOKIN; hexokinase; HK; Hk-1; HK1; Hk1-s; HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1; mHk1-s; NEDVIBA; NMSR; RP79
UniProt ID: (Human) P19367, (Rat) P05708, (Mouse) P17710
Entrez Gene ID: (Human) 3098, (Rat) 25058, (Mouse) 15275
nucleotide binding
catalytic activity
glucokinase activity
hexokinase activity
protein binding
ATP binding
glucose binding
fructokinase activity
kinase activity
transferase activity
phosphotransferase activity, alcohol group as acceptor
mannokinase activity
peptidoglycan binding
glucosamine kinase activity
protein kinase activity
ATPase activity
protein complex binding
protein homodimerization activity
kinase
cellular glucose homeostasis
immune system process
positive regulation of cytokine production involved in immune response
carbohydrate metabolic process
fructose 6-phosphate metabolic process
glucose metabolic process
mannose metabolic process
glycolytic process
inflammatory response
GDP-mannose biosynthetic process
hexose metabolic process
organophosphate metabolic process
positive regulation of interleukin-1 beta production
innate immune response
carbohydrate phosphorylation
glucose 6-phosphate metabolic process
canonical glycolysis
GDP-mannose biosynthetic process from mannose
establishment of protein localization to mitochondrion
maintenance of protein location in mitochondrion
carbohydrate derivative metabolic process
response to ischemia
protein phosphorylation
regulation of anion channel activity
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
peptidyl-tyrosine phosphorylation
negative regulation of apoptotic process
protein autophosphorylation
metabolic process
phosphorylation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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