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Invitrogen
SRC3 Monoclonal Antibody (5H3)
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Product Details
MA5-15898
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
5H3
Immunogen
Purified recombinant fragment of human AIB1 expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-15898 targets AIB1 in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15898 immunogen is purified recombinant fragment of human AIB1 expressed in E. Coli. .
MA5-15898 detects AIB1 which has a predicted molecular weight of approximately 155kDa.
Target Information
The poly Q polymorphism in AIB1 (amplified in breast cancer) gene is usually assessed by fragment length analysis which does not reveal the actual sequence variation. The purpose of this study is to investigate the sequence variation of poly Q encoding region in breast cancer cell lines at single molecule level, and to determine if the sequence variation is related to AIB1 gene amplification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ACTR; AIB-1; Amplified in breast cancer 1 protein; bHLHe42; CBP-interacting protein; Class E basic helix-loop-helix protein 42; NCoA-3; nuclear hormone receptor coactivator protein; nuclear receptor co-activator; Nuclear receptor coactivator 3; pCIP; RAC-3; Receptor-associated coactivator 3; SRC-3; Steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TRAM-1; unnamed protein product
Gene Aliases: ACTR; AIB-1; AIB1; BHLHE42; CAGH16; CTG26; KAT13B; NCOA3; pCIP; RAC3; SRC-3; SRC3; TNRC14; TNRC16; TRAM-1; TRAM1
UniProt ID: (Human) Q9Y6Q9
Entrez Gene ID: (Human) 8202
RNA polymerase II core binding
transcription cofactor activity
transcription coactivator activity
histone acetyltransferase activity
protein binding
transferase activity
transferase activity, transferring acyl groups
ligand-dependent nuclear receptor binding
thyroid hormone receptor binding
protein dimerization activity
peptide-lysine-N-acetyltransferase activity
disordered domain specific binding
chromatin remodeling
regulation of transcription, DNA-templated
cellular response to hormone stimulus
cell dedifferentiation
positive regulation of keratinocyte differentiation
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
vitamin D receptor signaling pathway
cellular response to estradiol stimulus
nucleus-associated proteasomal ubiquitin-dependent protein catabolic process
positive regulation of stem cell population maintenance
regulation of stem cell division
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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