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Invitrogen
Nucleostemin Monoclonal Antibody (2C8D5)
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Product Details
MA5-17082
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2C8D5
Immunogen
Purified recombinant fragment of human GNL3 (amino acids: 1-226) expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-17082 targets GNL3 in FACS, indirect ELISA, and WB applications and shows reactivity with Human and Mouse samples.
The MA5-17082 immunogen is purified recombinant fragment of human GNL3 (amino acids: 1-226) expressed in E. Coli.
MA5-17082 detects GNL3 which has a predicted molecular weight of approximately 62kDa.
Target Information
Arylsulfatase F, also known as ARSF, is a 590 amino acid secretory protein that belongs to the sulfatase family of bone and cartilage matrix proteins. Arylsulfatase F uses calcium as a cofactor to catalyze reactions that are important in maintaining correct bone composition. The activity of Arylsulfatase F, unlike that of other family members, such as Arylsulfatase E, is not inhibited by warfarin. The gene encoding Arylsulfatase F maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E2-induced gene 3 protein; estradiol-induced nucleotide binding protein; guanine nucleotide binding protein-like 3 (nucleolar); Guanine nucleotide-binding protein-like 3; MGC800; NNP47; Novel nucleolar protein 47; Nucleolar GTP-binding protein 3; Nucleostemin; unnamed protein product
Gene Aliases: C77032; E2IG3; GNL3; NNP47; NS; Nug1
UniProt ID: (Human) Q9BVP2, (Mouse) Q8CI11
Entrez Gene ID: (Human) 26354, (Mouse) 30877
cell proliferation
regulation of cell proliferation
ribosome biogenesis
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
stem cell division
stem cell population maintenance
positive regulation of telomere maintenance
positive regulation of protein sumoylation
positive regulation of protein localization to chromosome, telomeric region
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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