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Invitrogen
Claudin 6 Monoclonal Antibody (342927)
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Product Details
MA5-24076
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Amphibian
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
342927
Immunogen
NS0 mouse myeloma cell line transfected with human Claudin-6 Met1-Val220
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody stains human Claudin-6 transfected cells but not irrelevant transfectants.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Claudin-6; Claudin6; CLD6; Skullin; transmembrane protein; unnamed protein product
Gene Aliases: CLDN6; UNQ757/PRO1488
UniProt ID: (Human) P56747
Entrez Gene ID: (Human) 9074
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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