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Invitrogen
C3a Receptor Monoclonal Antibody (534625)
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FIGURE: 1 / 1
C3a Receptor Antibody (MA5-24235) in Flow
Flow cytometry of C3a Receptor in Human blood‚derived monocytes. Samples were incubated in C3a Receptor monoclonal antibody (Product # MA5-24235) or isotype control antibody followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab)2 Secondary Antibody.
Product Details
MA5-24235
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
534625
Immunogen
NS0 mouse myeloma cell line transfected with human C3a R Met1-Val482
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
C3AR1 is a receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. The receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C3a anaphylatoxin chemotactic receptor; C3a receptor; C3AR; complement component 3 receptor 1; complement component 3a receptor 1; putative G protein-coupled receptor; similar to human C5A anaphylatoxin chemotactic receptor, Swiss-Prot Accession Number P21730; unnamed protein product
Gene Aliases: AZ3B; C3AR; C3AR1; C3R1; HNFAG09
UniProt ID: (Human) Q16581
Entrez Gene ID: (Human) 719
complement receptor mediated signaling pathway
positive regulation of immune system process
chemotaxis
inflammatory response
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood circulation
positive regulation of vascular endothelial growth factor production
positive regulation of macrophage chemotaxis
calcium-mediated signaling
complement component C5a signaling pathway
positive regulation of angiogenesis
positive regulation of neutrophil chemotaxis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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