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          • Primary Antibodies ›
          • TTLL12 Antibodies

          Invitrogen

          TTLL12 Monoclonal Antibody (OTI4B2)

          1 Published Figure
          2 References
          View all (8) TTLL12 antibodies

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          Cite TTLL12 Monoclonal Antibody (OTI4B2)

          Additional Information:
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          {{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
          • Antibody Testing Data (17)
          • Published Figures (1)
          TTLL12 Antibody in Immunocytochemistry (ICC/IF)
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          TTLL12 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 18

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          TTLL12 Antibody (MA5-25018) in ICC/IF

          Immunofluorescent analysis of TTLL12 in HepG2 cells. Cells were probed with a TTLL12 monoclonal antibody (Product # MA5-25018). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          TTLL12 Antibody in Immunocytochemistry (ICC/IF)
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Western Blot (WB)
          TTLL12 Antibody in Western Blot (WB)
          TTLL12 Antibody in Western Blot (WB)
          TTLL12 Monoclonal Antibody (OTI4B2)

          Product Details

          MA5-25018

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000
          View 1 publication 1 publication

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50
          -

          Immunocytochemistry (ICC/IF)

          1:100
          -

          Flow Cytometry (Flow)

          1:100
          -
          Product Specifications

          Species Reactivity

          Human, Rat

          Published species

          Human

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          OTI4B2

          Immunogen

          Full length human recombinant protein of TTLL12 produced in HEK293T cell
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.73 mg/mL

          Amount

          73 µg

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 1% BSA, 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2723743

          Target Information

          TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: dJ526I14.2; Inactive tubulin--tyrosine ligase-like protein 12; KIAA0153; tubulin tyrosine ligase-like family, member 12; Tubulin--tyrosine ligase-like protein 12; unnamed protein product

          View more View less

          Gene Aliases: dJ526I14.2; KIAA0153; RGD1305319; TTLL12

          View more View less

          UniProt ID: (Human) Q14166

          View more View less

          Entrez Gene ID: (Human) 23170, (Rat) 300105

          View more View less

          Function(s)
          nucleotide binding tubulin-tyrosine ligase activity protein binding ATP binding histone H4K20me2 reader activity histone H4K20 trimethyltransferase activity
          Process(es)
          immune system process chromatin organization regulation of mitotic cell cycle innate immune response negative regulation of type I interferon-mediated signaling pathway cellular protein modification process
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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