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Invitrogen
NPR3 Monoclonal Antibody (OTI11H6)
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Product Details
MA5-25079
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI11H6
Immunogen
Full length human recombinant protein of NPR3 produced in HEK293T cell
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A NPR-C; ANP-C; Atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide receptor 3; Atrial natriuretic peptide receptor type C; atrionatriuretic peptide receptor C; guanylate cyclase C; natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C); unnamed protein product
Gene Aliases: ANP-C; ANPR-C; ANPRC; BOMOS; C5orf23; GUCY2B; NPR-C; NPR3; NPRC
UniProt ID: (Human) P17342
Entrez Gene ID: (Human) 4883
skeletal system development
angiogenesis
blood vessel remodeling
osteoclast proliferation
response to ischemia
cGMP biosynthetic process
signal transduction
G-protein coupled receptor signaling pathway
regulation of blood pressure
regulation of osteoblast proliferation
positive regulation of urine volume
negative regulation of cold-induced thermogenesis
positive regulation of relaxation of smooth muscle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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