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Invitrogen
DDX56 Monoclonal Antibody (OTI2E5)
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FIGURE: 1 / 14
DDX56 Antibody (MA5-26555) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human endometrium tissue. To expose target proteins, 10mM citric buffer, pH6.0, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a DDX56 monoclonal antibody (Product # MA5-26555).
Product Details
MA5-26555
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2E5
Immunogen
Human recombinant protein fragment corresponding to amino acids 323-547 of DDX56 produced in E.coli
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during assembly of the large 60S ribosomal subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 61-kd nucleolar helicase; ATP-dependent 61 kDa nucleolar RNA helicase; DDX21; DDX56; DEAD (Asp-Glu-Ala-Asp) box helicase 56; DEAD (Asp-Glu-Ala-Asp) box polypeptide 56; DEAD box protein 21; DEAD box protein 56; DEAD-box RNA helicase; nucleolar helicase of 61 kDa; Probable ATP-dependent RNA helicase DDX56; putative nucleolar RNA helicase; unnamed protein product
Gene Aliases: DDX21; DDX26; DDX56; NOH61
UniProt ID: (Human) Q9NY93
Entrez Gene ID: (Human) 54606
cytoplasmic pattern recognition receptor signaling pathway
rRNA processing
protein import into nucleus
positive regulation of neuron projection development
negative regulation of type I interferon production
ribosome biogenesis
modulation by host of viral RNA genome replication
defense response to virus
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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