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          • Primary Antibodies ›
          • PYCR1 Antibodies

          Invitrogen

          PYCR1 Monoclonal Antibody (OTI4F2)

          View all (16) PYCR1 antibodies

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          Cite PYCR1 Monoclonal Antibody (OTI4F2)

          Additional Information:
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          • Antibody Testing Data (7)
          PYCR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          PYCR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          PYCR1 Antibody (MA5-27523) in IHC (P)

          Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human breast tissue. To expose target proteins, heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min. Following antigen retrieval, tissues were probed with a PYCR1 monoclonal antibody (Product # MA5-27523) at a dilution of 1:500. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PYCR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PYCR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PYCR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PYCR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PYCR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PYCR1 Antibody in Western Blot (WB)
          PYCR1 Antibody in Western Blot (WB)
          PYCR1 Monoclonal Antibody (OTI4F2)

          Product Details

          MA5-27523

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          OTI4F2

          Immunogen

          Human recombinant protein fragment corresponding to amino acids 1-319 of PYCR1 produced in E.coli
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 1% BSA, 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2725157

          Target Information

          This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: P5C reductase 1; proliferation-inducing protein 45; PYCR1; Pyrroline-5-carboxylate reductase 1, mitochondrial; unnamed protein product

          View more View less

          Gene Aliases: ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR; PYCR1

          View more View less

          UniProt ID: (Human) P32322

          View more View less

          Entrez Gene ID: (Human) 5831

          View more View less

          Function(s)
          pyrroline-5-carboxylate reductase activity protein binding oxidoreductase activity identical protein binding
          Process(es)
          proline biosynthetic process cellular amino acid biosynthetic process cellular response to oxidative stress regulation of mitochondrial membrane potential L-proline biosynthetic process negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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