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Invitrogen
ACADM Monoclonal Antibody (OTI2G7)
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FIGURE: 1 / 7
ACADM Antibody (MA5-27524) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human breast tissue. To expose target proteins, heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min. Following antigen retrieval, tissues were probed with a ACADM monoclonal antibody (Product # MA5-27524) at a dilution of 1:500.
Product Details
MA5-27524
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2G7
Immunogen
Full length human recombinant protein of ACADM produced in HEK293T cell
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acyl-CoA dehydrogenase, C-4 to C-12 straight chain; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain; FLJ18227; FLJ93013; FLJ99884; MCAD; MCADH; Medium chain acyl-CoA dehydrogenase; medium-chain acyl-CoA dehydrogenase; medium-chain acyl-CoA dehydrogenase (EC 1.3.99.3); Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; RP4-682C21.1; testicular tissue protein Li 7; unnamed protein product
Gene Aliases: ACAD1; ACADM; MCAD; MCADH
UniProt ID: (Human) P11310
Entrez Gene ID: (Human) 34
liver development
glycogen biosynthetic process
organic acid metabolic process
regulation of gluconeogenesis
lipid metabolic process
fatty acid metabolic process
fatty acid beta-oxidation
heart development
response to cold
carnitine metabolic process
post-embryonic development
carnitine metabolic process, CoA-linked
fatty acid beta-oxidation using acyl-CoA dehydrogenase
response to starvation
carnitine biosynthetic process
medium-chain fatty acid metabolic process
medium-chain fatty acid catabolic process
cardiac muscle cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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