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Invitrogen
MHC Class II Monoclonal Antibody (2G11), FITC
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Product Details
MA5-28820
Product Specifications
Species Reactivity
Avian,
Chicken,
Reptile
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2G11
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5 mg/mL
Amount
500 µg
Purification
purified
Storage buffer
PBS, pH 7.4
Contains
<0.1% sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-L beta chain; B-L beta minor; B-LB21 major; beta 1 domain; Bl-Beta II protein; BLB major; major histocompatibility class II antigen B-L beta; major histocompatibility complex class II B; MHC 2; MHC Class II; MHC class II antigen B-F minor heavy chain; MHC class II antigen beta chain; MHC class II B-L beta chain; MHC Class II beta 1 and 2 domains; MHC class II beta 1 domain; MHC class II beta chain 1; MHC class II beta chain 2; MHC II; MHCCII
Gene Aliases: B-L; B-LB; B-LB2; B-LB21; B-LBII; GSP-BLB1; GSP-BLB2; S19
Entrez Gene ID: (Chicken) 693256, (Chicken) 101747454, (Chicken) 425256
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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