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Invitrogen
CHRNA5 Monoclonal Antibody (8F11G8)
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FIGURE: 1 / 5
CHRNA5 Antibody (MA5-31688) in WB
Western blot analysis of CHRNA5 in membrane protein lysate of C6 (1), membrane protein lysate of SK-N-SH (2), membrane protein lysate of C6 (3), and C6 (4) cell lysate. Samples were incubated with CHRNA5 monoclonal antibody (Product # MA5-31688) using a dilution of 1:500-1:2000.
Product Details
MA5-31688
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
8F11G8
Immunogen
Purified recombinant fragment of human CHRNA5 (AA: extra 23-254) expressed in E. coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-31688 has been tested in indirect ELISA.
Target Information
Nicotinic acetylcholine receptors (nAChRs), such as CHRNA5, are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor; acetylcholine receptor alpha 5; acetylcholine receptor, nicotinic, alpha 5 (neuronal); cholinergic receptor; Cholinergic receptor, neuronal nicotinic, alpha polypeptide-5; cholinergic receptor, nicotinic alpha 5; cholinergic receptor, nicotinic, alpha 5 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 5; nAChR alpha 5; Neuronal acetylcholine receptor subunit alpha-5; neuronal nicotinic acetylcholine receptor, alpha5 subunit
Gene Aliases: CHRNA5; LNCR2; NACHRA5
UniProt ID: (Human) P30532
Entrez Gene ID: (Human) 1138, (Rat) 25102
transmembrane signaling receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
protein binding
ligand-gated ion channel activity
acetylcholine receptor activity
acetylcholine-gated cation channel activity
acetylcholine-activated cation-selective channel activity
acetylcholine binding
protein heterodimerization activity
ligand-gated ion channel
ion transport
signal transduction
chemical synaptic transmission
synaptic transmission, cholinergic
neuromuscular synaptic transmission
ion transmembrane transport
response to nicotine
behavioral response to nicotine
membrane depolarization
regulation of postsynaptic membrane potential
excitatory postsynaptic potential
acetylcholine receptor signaling pathway
presynaptic modulation of chemical synaptic transmission
cation transport
cation transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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