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Invitrogen
Vitronectin Recombinant Rabbit Monoclonal Antibody (ST49-02)
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FIGURE: 1 / 9
Vitronectin Antibody (MA5-32157) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Vitronectin in human liver tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS. Incubation was done with monoclonal Vitronectin antibody (Product # MA5-32157) at a dilution of 1:50 (30 min,... View More
Product Details
MA5-32157
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ST49-02
Immunogen
Synthetic peptide within Human Vitronectin aa 429-478.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: complement S-protein; epibolin; S-protein; serum spreading factor; Serum-spreading factor; somatomedin B; unnamed protein product; V75; Vitronectin; VN
Gene Aliases: Aa1018; AI256434; V75; VN; VNT; VTN
UniProt ID: (Human) P04004, (Mouse) P29788
Entrez Gene ID: (Human) 7448, (Rat) 29169, (Mouse) 22370
immune response
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
positive regulation of cell-substrate adhesion
positive regulation of smooth muscle cell migration
vesicle-mediated transport
cell migration
cell differentiation
regulation of cell adhesion
negative regulation of blood coagulation
extracellular matrix organization
positive regulation of vascular endothelial growth factor receptor signaling pathway
cell adhesion mediated by integrin
endodermal cell differentiation
negative regulation of proteolysis
positive regulation of receptor-mediated endocytosis
oligodendrocyte differentiation
protein polymerization
negative regulation of fibrinolysis
smooth muscle cell-matrix adhesion
positive regulation of wound healing
liver regeneration
positive regulation of vascular endothelial growth factor signaling pathway
positive regulation of integrin-mediated signaling pathway
receptor-mediated endocytosis
negative regulation of endopeptidase activity
positive regulation of protein binding
positive regulation of peptidyl-tyrosine phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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