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Invitrogen
Aquaporin 1 Recombinant Rabbit Monoclonal Antibody (JM10-98)
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FIGURE: 1 / 13
Aquaporin 1 Antibody (MA5-32593) in ICC/IF
Immunofluorescence analysis of AQP1 was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Aquaporin 1 Recombinant Rabbit Monoclonal Antibody (JM10-98) (Product # MA5-32593) at 5 µg/mL in 0.1% BSA, incubated a... View More
Product Details
MA5-32593
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JM10-98
Immunogen
Synthetic peptide within Human AQP1 aa 245-269.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 28 kda erythrocyte integral membrane protein homolog; AQP 1; AQP CHIP; AQP-1; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1, Colton blood group antigen; Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; bloodgroup CO protein; Channel-like integral membrane protein of 28 kDa; channel-like integral membrane protein, 28-kDa; CHIP 28; Colton blood group; Colton blood group antigen; Delayed early response protein 2; DER2; growth factor-induced delayed early response protein; MGC26324; unnamed protein product; Urine water channel; water channel protein for red blood cells and kidney proximal tubule
Gene Aliases: AQP-CHIP; AQP1; CHIP28; CO
UniProt ID: (Human) P29972, (Mouse) Q02013, (Rat) P29975
Entrez Gene ID: (Human) 358, (Mouse) 11826, (Rat) 25240
intracellular cGMP activated cation channel activity
potassium channel activity
water transmembrane transporter activity
protein binding
ammonium transmembrane transporter activity
potassium ion transmembrane transporter activity
glycerol transmembrane transporter activity
water channel activity
channel activity
transmembrane transporter activity
nitric oxide transmembrane transporter activity
carbon dioxide transmembrane transporter activity
identical protein binding
ephrin receptor binding
hydrogen peroxide channel activity
transporter activity
glycerol channel activity
transporter
renal water homeostasis
glomerular filtration
renal water transport
potassium ion transport
water transport
cell volume homeostasis
hyperosmotic response
cellular water homeostasis
fibroblast migration
positive regulation of fibroblast migration
carbon dioxide transport
glycerol transport
cell migration
sensory perception of pain
cellular homeostasis
cGMP-mediated signaling
lateral ventricle development
pancreatic juice secretion
nitric oxide transport
establishment or maintenance of actin cytoskeleton polarity
secretion by cell
cerebrospinal fluid secretion
secretory granule organization
cellular response to UV
transepithelial water transport
carbon dioxide transmembrane transport
wound healing
odontogenesis
negative regulation of apoptotic process
lipid digestion
positive regulation of angiogenesis
positive regulation of saliva secretion
positive regulation of fibroblast proliferation
camera-type eye morphogenesis
defense response to Gram-negative bacterium
multicellular organismal water homeostasis
corticotropin secretion
establishment of localization in cell
transmembrane transport
renal water absorption
cellular response to hydrogen peroxide
cellular response to mechanical stimulus
cellular response to copper ion
cellular response to mercury ion
cellular response to retinoic acid
cellular response to cAMP
cellular response to hypoxia
cellular response to salt stress
cellular hyperosmotic response
cellular response to dexamethasone stimulus
cellular response to nitric oxide
potassium ion transmembrane transport
metanephric descending thin limb development
metanephric proximal straight tubule development
metanephric proximal convoluted tubule segment 2 development
metanephric glomerulus vasculature development
ammonium transmembrane transport
hydrogen peroxide transmembrane transport
cation transmembrane transport
cGMP biosynthetic process
transport
positive regulation of lamellipodium assembly
positive regulation of epithelial cell migration
organic cation transport
ammonium transport
water homeostasis
positive regulation of cell migration
cellular response to stress
carbohydrate transmembrane transport
response to drug
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to inorganic substance
maintenance of symbiont-containing vacuole by host
response to hormone
hyperosmotic salinity response
response to estrogen
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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