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Invitrogen
COBRA1 Monoclonal Antibody (F7E4)
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Product Details
MA5-33101
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
F7E4
Immunogen
Recombinant full length human COBRA1 purified from E. coli
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2), either NELFC or NELFD (TH1L), and NELFE (RDBP), a heterodimer of SPT4 (SUPT4H1), to cause transcriptional pausing of RNA polymerase II (Narita et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cofactor of BRCA1; DKFZp586B0519; Negative elongation factor B; negative elongation factor complex member B, Cobra1; negative elongation factor protein B; NELF-B; ortholog of human cofactor of BRCA1 (COBRA1); RP13-122B23.3; unnamed protein product
Gene Aliases: A730008L03Rik; AB041607; AI663983; COBRA1; KIAA1182; MNCb-5210; NELF-B; NELFB; RGD1307832
UniProt ID: (Human) Q8WX92, (Mouse) Q8C4Y3
Entrez Gene ID: (Human) 25920, (Mouse) 58202, (Rat) 311796
cell proliferation
negative regulation of transcription elongation from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
stem cell differentiation
negative regulation of stem cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
translational elongation
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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