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Invitrogen
ADAMTS13 Recombinant Rabbit Monoclonal Antibody (JG39-21)
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Product Details
MA5-34796
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JG39-21
Immunogen
Synthetic peptide within Human ADAMTS13 aa 71-124.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: SiHa cell, PC-3M, A549, HepG2, human liver tissue, human colon tissue.
Target Information
ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 13; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13; ADAM; ADAM-TS 13; ADAMs; metalloendopeptidases; preproprotein; metalloprotease; unnamed protein product; von Willebrand factor-cleaving protease; vWF-cleaving protease; vWF-CP
Gene Aliases: ADAM-TS13; ADAMTS-13; ADAMTS13; C9orf8; UNQ6102/PRO20085; vWF-CP; VWFCP
UniProt ID: (Human) Q76LX8
Entrez Gene ID: (Human) 11093
proteolysis
cell-matrix adhesion
integrin-mediated signaling pathway
blood coagulation
hemostasis
glycoprotein metabolic process
response to toxic substance
response to amine
protein processing
protein catabolic process
platelet activation
extracellular matrix organization
response to interferon-gamma
response to tumor necrosis factor
response to potassium ion
peptide catabolic process
response to interleukin-4
cellular response to lipopolysaccharide
cellular response to interferon-gamma
cellular response to interleukin-4
cellular response to tumor necrosis factor
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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