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Invitrogen
CES1 Recombinant Rabbit Monoclonal Antibody (7C9R6)
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Product Details
MA5-35117
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
7C9R6
Immunogen
Synthetic peptide
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Amount
80 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MWLRAFILAT LSASAAWGHP SSPPVVDTVH GKVLGKFVSL EGFAQPVAIF LGIPFAKPPL GPLRFTPPQP AEPWSFVKNA TSYPPMCTQD PKAGQLLSEL
Target Information
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACAT; acyl coenzyme A:cholesterol acyltransferase; Acyl-coenzyme A:cholesterol acyltransferase; Brain carboxylesterase hBr1; Carboxyesterase ES-1; carboxyesterase ES-3; Carboxylesterase 1; carboxylesterase 1 (monocyte/macrophage serine esterase 1); carboxylesterase 1-like; Carboxylesterase 1C; Carboxylesterase 1E; Carboxylesterase 1G; carboxylesterase 2 (liver); carboxylesterase; ACAT; CE-1; CEH; Cholesteryl ester hydrolase; Cocaine carboxylesterase; E1; Egasyn; ER-resident carboxylesterase; Es-22; ES-HTEL; ES-THET; ES-x; esterase 1; Esterase 2 member of carboxylesterase-cluster 1; esterase 2, member of carboxylesterase-cluster 1; esterase 22; Esterase-2; esterase-22; HMSE; human monocyte/macrophage serine esterase 1; Liver carboxylesterase 1; Liver carboxylesterase 22; liver carboxylesterase 3; Liver carboxylesterase N; Lung surfactant convertase; Methylumbelliferyl-acetate deacetylase 1; MGC117365; Monocyte/macrophage serine esterase; Neutral retinyl ester hydrolase; NREH; PES-N; pI 5.5 esterase; REH; Retinyl ester hydrolase; Serine esterase 1; TGH; triacylglycero; Triacylglycerol hydrolase; unnamed protein product
Gene Aliases: ACAT; CE-1; CEH; Ces-1; Ces-N; CES1; Ces1c; Ces1e; Ces1g; Ces1l; CES2; Ee-1; Ee1; Eg; EG244595; egasyn; Es-22; Es-4; Es-N; Es1; Es2; Es22; Es4; EsN; Gm4976; hCE-1; HMSE; HMSE1; PCE-1; PESN; REH; Ses-1; SES1; TGH
UniProt ID: (Human) P23141, (Mouse) P23953, (Rat) P10959, (Mouse) Q64176, (Mouse) Q8VCC2
Entrez Gene ID: (Human) 1066, (Rat) 679817, (Mouse) 244595, (Mouse) 13884, (Rat) 24346, (Rat) 29225, (Mouse) 13897, (Mouse) 12623
lipid metabolic process
cholesterol biosynthetic process
cholesterol metabolic process
response to toxic substance
positive regulation of cholesterol efflux
negative regulation of cholesterol storage
lipid catabolic process
epithelial cell differentiation
cholesterol homeostasis
reverse cholesterol transport
medium-chain fatty acid metabolic process
regulation of bile acid biosynthetic process
cellular response to cholesterol
cellular response to low-density lipoprotein particle stimulus
cholesterol ester hydrolysis involved in cholesterol transport
positive regulation of cholesterol metabolic process
regulation of bile acid secretion
metabolic process
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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