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Invitrogen
C1 inhibitor Recombinant Rabbit Monoclonal Antibody (0D3W8)
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FIGURE: 1 / 1
C1 inhibitor Antibody (MA5-37889) in WB
Western blot analysis of C1 inhibitor in extracts of various cell lines. Samples were incubated with C1 inhibitor Monoclonal antibody (Product # MA5-37889) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
MA5-37889
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
0D3W8
Immunogen
Synthetic peptide
Conjugate
Form
Liquid
Concentration
3 mg/mL
Amount
300 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Human plasma, Mouse plasma, Rat plasma
Immunogen sequence: SLKLYHAFSA MKKVETNMAF SPFSIASLLT QVLLGAGENT KTNLESILSY PKDFTCVHQA LKGFTTKGVT SVSQIFHSPD LAIRDTFVNA SRTLYSSSPR V
Target Information
C1-inhibitor (C1INH) functions as a regulator of the activation of the classical complement pathway and of the contact activation system of kinin generation and coagulation. Its primary biologically relevant target proteinases are C1r, C1s, coagulation factors XIa and XIIa, and plasma kallikrein. C1-inhibitor consists of one polypeptide chain and has a molecular mass of ~104 kDa. Serum concentration has been determined to 180 µg/mL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C1 esterase inhibitor; C1 Inh; C1 inhibitor; C1-inhibiting factor; C1-inhibitor; C1Inh; complement component 1 inhibitor; epididymis secretory sperm binding protein; esterase inhibitor; IC1; plasma protease (C1) inhibitor precursor; Plasma protease C1 inhibitor; serine (or cysteine) peptidase inhibitor, clade G, member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary); serine (or cysteine) proteinase inhibitor, clade G, member 1; serine/cysteine proteinase inhibitor clade G member 1; Serpin G1; serpin peptidase inhibitor clade G (C1 inhibitor) member 1 isoform SERPING1_1; serpin peptidase inhibitor clade G (C1 inhibitor) member 1 isoform SERPING1_2; serpin peptidase inhibitor clade G (C1 inhibitor) member 1 isoform SERPING1_3; serpin peptidase inhibitor clade G (C1 inhibitor) member 1 isoform SERPING1_4; serpin peptidase inhibitor clade G member 1; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; serpin peptidase inhibitor, clade G, member 1; SERPING1; unnamed protein product
Gene Aliases: C1IN; C1INH; C1NH; HAE1; HAE2; SERPING1
UniProt ID: (Human) P05155, (Rat) Q6P734, (Mouse) P97290
Entrez Gene ID: (Human) 710, (Rat) 295703, (Mouse) 12258
negative regulation of complement activation, lectin pathway
blood coagulation
hemostasis
blood circulation
fibrinolysis
complement activation, classical pathway
aging
biological_process
negative regulation of endopeptidase activity
innate immune response
immune system process
negative regulation of peptidase activity
regulation of blood coagulation
negative regulation of complement activation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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