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Invitrogen
SLC22A3 Recombinant Rabbit Monoclonal Antibody (1K0A4)
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FIGURE: 1 / 3
SLC22A3 Antibody (MA5-37983) in IHC (P)
Immunohistochemistry analysis of SLC22A3 in paraffin-embedded human liver cancer. Samples were incubated with SLC22A3 Monoclonal antibody (Product # MA5-37983) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
MA5-37983
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1K0A4
Immunogen
Recombinant protein (or fragment)
Conjugate
Form
Liquid
Concentration
0.32 mg/mL
Amount
32 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: PC-3, Mouse liver
Immunogen sequence: GDKALQILRR IAKCNGKYLS SNYSEITVTD EEVSNPSFLD LVRTPQMRKC TLILMFAWFT SAVVYQGLVM RLGIIGGNLY IDFFISGVVE LPGALLILLT IERLGRRLPF AASNIVAGVA CLVTAFLPEG IAWLRTTVAT LGRLGITMAF
Target Information
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-Oct; EMT; EMT organic cation transporter 3; Extraneuronal monoamine transporter; OCT3; Organic cation transporter 3; solute carrier family 22 (extraneuronal monoamine transporter), member 3; solute carrier family 22 (organic cation transporter), member 3; Solute carrier family 22 member 3; solute carrier family 22, member 3; unnamed protein product
Gene Aliases: EMT; EMTH; OCT3; Orct3; SLC22A3; Slca22a3
UniProt ID: (Human) O75751, (Mouse) Q9WTW5
Entrez Gene ID: (Human) 6581, (Mouse) 20519
neurotransmitter transporter activity
protein binding
monoamine transmembrane transporter activity
organic anion transmembrane transporter activity
organic cation transmembrane transporter activity
spermidine transmembrane transporter activity
quaternary ammonium group transmembrane transporter activity
toxin transporter activity
transmembrane transporter activity
transporter activity
dopamine transmembrane transporter activity
ion transmembrane transporter activity
secondary carrier transporter
histamine metabolic process
ion transport
neurotransmitter transport
serotonin transport
organic cation transport
quaternary ammonium group transport
organic anion transport
monocarboxylic acid transport
monoamine transport
spermidine transport
organic hydroxy compound transport
dopamine transport
norepinephrine transport
regulation of appetite
xenobiotic transport
epinephrine transport
histamine transport
serotonin uptake
histamine uptake
norepinephrine uptake
epinephrine uptake
establishment of localization in cell
transmembrane transport
purine-containing compound transmembrane transport
dopamine uptake
transport across blood-brain barrier
spermidine transmembrane transport
cellular detoxification
transport
ion transmembrane transport
ammonium transmembrane transport
cation transmembrane transport
mitophagy in response to mitochondrial depolarization
toxin transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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