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Invitrogen
SMC4 Recombinant Rabbit Monoclonal Antibody (9Z8S3)
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Product Details
MA5-38079
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
9Z8S3
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1189-1288 of human SMC4 (Q9NTJ3)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: HT-29, NIH/3T3, Raji, C6, Mouse testis, Mouse thymus, Rat testis
Immunogen sequence: FNLSGGEKTL SSLALVFALH HYKPTPLYFM DEIDAALDFK NVSIVAFYIY EQTKNAQFII ISLRNNMFEI SDRLIGIYKT YNITKSVAVN PKEIASKGLC
Target Information
The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chromosome-associated polypeptide C; hCAP-C; SMC protein 4; SMC4 structural maintenance of chromosomes 4-like 1; structural maintenance of chromosomes (SMC) family member; Structural maintenance of chromosomes protein 4; unnamed protein product; XCAP-C homolog
Gene Aliases: 2500002A22Rik; C79747; CAP-C; CAPC; SMC-4; SMC4; SMC4L1
UniProt ID: (Human) Q9NTJ3, (Mouse) Q8CG47
Entrez Gene ID: (Human) 10051, (Mouse) 70099, (Rat) 295107
cell cycle
mitotic nuclear division
mitotic chromosome condensation
meiotic chromosome condensation
chromosome condensation
meiotic chromosome segregation
chromosome organization
cell division
kinetochore organization
mitotic sister chromatid segregation
nuclear division
positive regulation of chromosome segregation
nuclear chromosome segregation
positive regulation of chromosome separation
positive regulation of chromosome condensation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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