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Invitrogen
Adenosine Deaminase Recombinant Rabbit Monoclonal Antibody (5R10B4)
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FIGURE: 1 / 2
Adenosine Deaminase Antibody (MA5-38137) in WB
Western blot analysis of Adenosine Deaminase in various lysates. Samples were incubated with Adenosine Deaminase Monoclonal antibody (Product # MA5-38137) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Product Details
MA5-38137
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
5R10B4
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human Adenosine Deaminase (ADA) (NP_0000132)
Conjugate
Form
Liquid
Concentration
3 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Jurkat, Mouse stomach
Immunogen sequence: NRLRQENMHF EICPWSSYLT GAWKPDTEHA VIRLKNDQAN YSLNTDDPLI FKSTLDTDYQ MTKRDMGFTE EEFKRLNINA AKSSFLPEDE KRELLDLLYK A
Target Information
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenosine aminohydrolase; Adenosine deaminase; RP11-61L14.5
Gene Aliases: ADA; ADA1
UniProt ID: (Human) P00813, (Mouse) P03958
Entrez Gene ID: (Human) 100, (Mouse) 11486
allantoin metabolic process
response to hypoxia
in utero embryonic development
trophectodermal cell differentiation
liver development
placenta development
germinal center B cell differentiation
germinal center formation
positive regulation of germinal center formation
negative regulation of leukocyte migration
mature B cell apoptotic process
negative regulation of mature B cell apoptotic process
adenosine catabolic process
deoxyadenosine catabolic process
AMP catabolic process
xenobiotic metabolic process
apoptotic process
smooth muscle contraction
cell adhesion
nucleotide metabolic process
purine ribonucleoside monophosphate biosynthetic process
positive regulation of heart rate
response to purine-containing compound
calcium-mediated signaling
T cell differentiation
lung development
positive regulation of B cell proliferation
purine nucleotide salvage
GMP salvage
T cell differentiation in thymus
positive regulation of T cell differentiation in thymus
regulation of cell-cell adhesion mediated by integrin
B cell proliferation
T cell activation
negative regulation of apoptotic process
penile erection
purine-containing compound salvage
hypoxanthine salvage
cellular amide catabolic process
AMP salvage
regulation of circadian sleep/wake cycle, sleep
regulation of T cell differentiation
positive regulation of T cell differentiation
positive regulation of smooth muscle contraction
dAMP catabolic process
dATP catabolic process
adenosine metabolic process
hypoxanthine biosynthetic process
inosine biosynthetic process
xanthine biosynthetic process
alpha-beta T cell differentiation
positive regulation of alpha-beta T cell differentiation
lung alveolus development
Peyer's patch development
embryonic digestive tract development
negative regulation of inflammatory response
positive regulation of calcium-mediated signaling
T cell receptor signaling pathway
positive regulation of T cell receptor signaling pathway
positive regulation of T cell activation
leukocyte migration
negative regulation of adenosine receptor signaling pathway
negative regulation of penile erection
thymocyte apoptotic process
negative regulation of thymocyte apoptotic process
mucus secretion
negative regulation of mucus secretion
histamine secretion
response to vitamin E
negative regulation of circadian sleep/wake cycle, non-REM sleep
response to morphine
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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