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Invitrogen
AIM2 Monoclonal Antibody (3C4G11)
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FIGURE: 1 / 5
AIM2 Antibody (MA5-38442) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of AIM2 in MCF-7 cells using AIM2 Monoclonal Antibody (Product # MA5-38442) (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Product # 35503)
Product Details
MA5-38442
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3C4G11
Immunogen
Purified recombinant fragment of human AIM2 (aa: 1-195) expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Absent in melanoma 2; Interferon-inducible protein AIM2; RP11-520H16.3; unnamed protein product
Gene Aliases: AIM2; PYHIN4
UniProt ID: (Human) O14862
Entrez Gene ID: (Human) 9447
activation of innate immune response
pattern recognition receptor signaling pathway
positive regulation of defense response to virus by host
immune system process
inflammatory response
immune response
cellular response to DNA damage stimulus
brain development
negative regulation of NF-kappaB transcription factor activity
positive regulation of interleukin-1 beta production
tumor necrosis factor-mediated signaling pathway
cellular response to interferon-beta
T cell homeostasis
innate immune response
positive regulation of inflammatory response
regulation of behavior
positive regulation of NF-kappaB transcription factor activity
protein maturation
defense response to virus
negative regulation of protein kinase B signaling
neuron cellular homeostasis
pyroptosis
cellular response to cytokine stimulus
cellular response to xenobiotic stimulus
AIM2 inflammasome complex assembly
pyroptotic cell death
pyroptosome complex assembly
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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