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Invitrogen
SMYD3 Recombinant Rabbit Monoclonal Antibody (JM73-63)
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FIGURE: 1 / 9
SMYD3 Antibody (MA5-41238) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of SMYD3 in HepG2 cells (green) using SMYD3 Recombinant Monoclonal Antibody (Product # MA5-41238). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. The nuclear counter stain is DAPI (blue).
Product Details
MA5-41238
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JM73-63
Immunogen
Synthetic peptide within Human SMYD3 aa 251-300.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
SMYD3 (histone-lysine N-methyltransferase) methylates Lys-4 of histone H3 and Lys-5 of histone H4. It induces di- and tri-methylation. SMYD3 plays an important role in transcriptional activation as a member of an RNA polymerase complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Histone-lysine N-methyltransferase SMYD3; SET and MYND domain-containing protein 3; SET domain; unnamed protein product; Zinc finger MYND domain-containing protein 1; zinc finger protein, subfamily 3A (MYND domain containing), 1; zinc finger, MYND domain containing 1
Gene Aliases: 2410008A19Rik; bA74P14.1; KMT3E; SMYD3; ZMYND1; ZNFN3A1
UniProt ID: (Human) Q9H7B4, (Mouse) Q9CWR2
Entrez Gene ID: (Human) 64754, (Mouse) 69726, (Rat) 498295
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core binding
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
protein binding
methyltransferase activity
zinc ion binding
transferase activity
histone methyltransferase activity
metal ion binding
histone H4 methyltransferase activity
histone H3K36 dimethyltransferase activity
histone H3K4 trimethyltransferase activity
RNA polymerase II core promoter sequence-specific DNA binding
histone-lysine N-methyltransferase activity
molecular_function
histone modifying enzyme
chromatin organization
nucleosome assembly
myotube cell development
methylation
establishment of protein localization
positive regulation of transcription from RNA polymerase II promoter
cellular response to dexamethasone stimulus
negative regulation of protein kinase activity
chromatin modification
positive regulation of peptidyl-serine phosphorylation
histone lysine methylation
biological_process
peptidyl-lysine methylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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