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Invitrogen
Blood Group A Antigen Monoclonal Antibody (HE-195)
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FIGURE: 1 / 2
Blood Group A Antigen Antibody (MA5-44036) in Flow
Separation of erythrocytes stained anti-human Blood Group A (HE-195) purified Monoclonal antibody (Product # MA5-44036), concentration in sample 3.3 µg/mL, GAM APC (red-filled) from erythrocytes unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining).
Product Details
MA5-44036
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgM
Class
Monoclonal
Type
Antibody
Clone
HE-195
Immunogen
Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
sequential chromatography
Storage buffer
TBS, pH 8
Contains
15mM sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody recognizes human blood group A including weak variants A3, AX, A3B, AXB. The specifity of antibody HE-195 was confirmed by comparison of specifity and reactivity to standard reagent using >5000 samples of blood.
Target Information
Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A transferase; ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase); alpha 1-3-N-acetylgalactosaminyltransferase; Any polymorphism or mutation that changes the activity or specificity of the encoded enzyme may therefore alter the ABO phenotype.; B transferase; B(A) alpha-1,3-galactosyltransferase; Bel; Blood Group A1; Blood Group A2; Blood Group A3; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; Histo-blood group A transferase; histo-blood group A transferase (UDP-GalNAc); histo-blood group A2 transferase; Histo-blood group ABO system transferase; Histo-blood group B transferase; NAGAT; transferase A; A glycosyltransferase; transferase B; Unknown; unnamed protein product
Gene Aliases: A3GALNT; A3GALT1; ABO; GTB; NAGAT
UniProt ID: (Human) P16442
Entrez Gene ID: (Human) 28
nucleotide binding
antigen binding
glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity
fucosylgalactoside 3-alpha-galactosyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring hexosyl groups
manganese ion binding
metal ion binding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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