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Invitrogen
FKBP5 Monoclonal Antibody (Hi51B), FITC
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FIGURE: 1 / 1
FKBP5 Antibody (MA5-45161) in WB
Western Blot analysis of Human Cervical cancer cell line (HeLa) lysate showing detection of FKBP51 protein. Load: 15 µg. Blocking: 1.5% BSA for 30 minutes at RT. Samples were incubated with FKBP51 monoclonal antibody (Product # MA5-45161) at 1:1,000 for 2 hours at RT, followed by Sheep Anti-Mouse IgG: HRP for 1 hour at RT.
Product Details
MA5-45161
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Hamster,
Human,
Mouse,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
Hi51B
Immunogen
Synthetic peptide corresponding to the residues of human FKBP51
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
9.09mM sodium bicarbonate/PBS with 640.91mM DMSO, 136.36mM ethanolamine
Contains
no preservative
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A 1:2,000 dilution was sufficient for detection of FKBP51 in approximately 50 µg total protein using WB analysis.|Detects approximately 51kDa.
Target Information
FKBP5 is a member of the immunophilin protein family. This family plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP5 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. The gene that encodes FKBP5 has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 51 kDa FK506-binding protein; 51 kDa FKBP; 54 kDa progesterone receptor-associated immunophilin; Androgen-regulated protein 6; EC 5.2.1.8; FF1 antigen; FK506 binding protein 5; FK506-binding protein 5; FKBP-5; FKBP-51; FKBP54; HSP90-binding immunophilin; p54; Peptidyl-prolyl cis-trans isomerase FKBP5; peptidylprolyl cis-trans isomerase; peptidylprolyl isomerase; PPIase FKBP5; Rotamase; T-cell FK506-binding protein; unnamed protein product
Gene Aliases: AIG6; D17Ertd592e; Dit1; FKBP-5; FKBP5; FKBP51; FKBP54; P54; PPIase; Ptg-10
UniProt ID: (Human) Q13451, (Mouse) Q64378, (Rat) Q5U2T9
Entrez Gene ID: (Rabbit) 100339155, (Human) 2289, (Dog) 481759, (Mouse) 14229, (Rat) 361810, (Chinese hamster) 100760904
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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