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Invitrogen
AIP Monoclonal Antibody (10G8)
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FIGURE: 1 / 7
AIP Antibody (MA5-49238) in ICC/IF
Immunocytochemistry analysis of AIP in A431 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum. Samples were then incubated in AIP Monoclonal antibody (Product # MA5-49238) using a dilution of 2 μg/mL. DyLight®488 Conjugated Goat Anti-Mouse IgG was used as secondary antibody at 1:100 dilution and incubated for 30 minutes at 37°C. The section was counterstained with DAPI. Visualize using a fluorescence microscope and filter sets appropriate for the... View More
Product Details
MA5-49238
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
10G8
Immunogen
E.coli-derived human ARA9 recombinant protein (Position: D91-H330).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Human ARA9 shares 95% amino acid (aa) sequence identity with both mouse and rat ARA9.
Positive Control - WB: human HELA whole cell, human HEPG2 whole cell, human placenta tissue, human CACO-2 whole cell, human U20S whole cell, monkey COS-7 whole cell, human K562 whole cell, rat heart tissue, rat skeletal muscle tissue, rat brain tissue, rat spleen tissue, mouse brain tissue, mouse HEPA1-6 whole cell. IHC: human intestinal cancer tissue, human tonsil tissue, rat spleen tissue. ICC/IF: A431 cell. Flow: A549 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ah receptor activated 9; AH receptor-interacting protein; AIP; aryl hydrocarbon receptor interacting protein; aryl hydrocarbon receptor-associated protein 9; Aryl-hydrocarbon receptor-interacting protein; FK506-binding protein 37; FKBP prolyl isomerase 16; HBV X-associated protein 2; HBV-X associated protein; hepatitis B virus X-associated cellular protein 2; Immunophilin homolog ARA9; Immunophilin XAP2; X-associated protein-2; XAP-2
Gene Aliases: AA408703; AIP; ARA9; AW476050; D19Bwg1412e; FKBP16; FKBP37; PITA1; SMTPHN; XAP-2; XAP2
UniProt ID: (Human) O00170, (Mouse) O08915, (Rat) Q5FWY5
Entrez Gene ID: (Human) 9049, (Mouse) 11632, (Rat) 282827
protein targeting to mitochondrion
xenobiotic metabolic process
positive regulation of transcription, DNA-templated
protein maturation
protein folding
regulation of protein kinase A signaling
protein maturation by protein folding
negative regulation of cyclic-nucleotide phosphodiesterase activity
regulation of nucleic acid-templated transcription
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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