Search
Invitrogen
Cystatin C Monoclonal Antibody (KT145)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 2
Cystatin C Antibody (MA5-49516) in IHC (P)
Immunohistochemistry analysis of Cystatin C in formalin-fixed paraffin-embedded human kidney tissue. Samples were incubated in Cystatin C monoclonal antibody (Product # MA5-49516) using a dilution of 2 µg/mL at room temperature for 1 hour followed by poly-peroxidase conjugated goat anti-mouse IgG secondary antibody. Antigen was retrieved thorough addition of boiling Tris/EDTA buffer pH 9 in a pressure cooke... View More
Product Details
MA5-49516
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
KT145
Immunogen
Purified native human Cystatin-C
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This product was used in both Indirect and Sandwich ELISA.
Target Information
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: AD8; bA218C14.4 (cystatin C); CST3; cystatin 3; Cystatin-3; Cystatin-C; Cystatin3; CystatinC; epididymis secretory protein Li 2; Gamma-trace; MGC117328; Neuroendocrine basic polypeptide; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; Post-gamma-globulin; RP23-250M11.9; unnamed protein product
Gene Aliases: ADLDWA; ARMD11; CST3; HEL-S-2
UniProt ID: (Human) P01034
Entrez Gene ID: (Human) 1471
defense response
immune response
negative regulation of collagen catabolic process
negative regulation of extracellular matrix disassembly
regulation of tissue remodeling
negative regulation of proteolysis
negative regulation of elastin catabolic process
negative regulation of blood vessel remodeling
fibril organization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support