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Invitrogen
GSTM3 Monoclonal Antibody (2H9D7)
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FIGURE: 1 / 3
GSTM3 Antibody (MA5-50283) in IHC (P)
Immunohistochemistry analysis with a GSTM3 monoclonal antibody (Product # MA5-50283) using a dilution of 1:100 and staining in paraffin-embedded human testes tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 min at RT. Then primary antibody (1% BSA) was incub... View More
Product Details
MA5-50283
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2H9D7
Immunogen
Recombinant Human Glutathione S-transferase Mu 3 protein (1-225AA)
Conjugate
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% Proclin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Glutathione S-transferase M3 (brain), also known as GSTM3, is an enzyme which in humans is encoded by theGSTM3 gene. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13. 3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: brain GST; brain type mu-glutathione S-transferase; cytosolic and membrane-bound form; GSTM3-related polypeptide; epididymis secretory sperm binding protein; glutathione S-alkyltransferase M3; glutathione S-aralkyltransferase M3; glutathione S-aryltransferase M3; glutathione S-transferase M3 (brain); Glutathione S-transferase Mu 3; glutathione S-transferase mu 3 (brain); glutathione S-transferase, Mu-3; GST class-mu 3; GSTM3; GSTM3-3; hGSTM3-3; S-(hydroxyalkyl)glutathione lyase M3; unnamed protein product
Gene Aliases: GST5; GSTB; GSTM3; GSTM3-3; GSTM3TV2; GTM3; hGSTM3-3
UniProt ID: (Human) P21266
Entrez Gene ID: (Human) 2947
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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