Search
Invitrogen
WNT8A Recombinant Rabbit Monoclonal Antibody (HL1648)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 4
WNT8A Antibody (MA5-50327) in ICC/IF
Immunocytochemical analysis of WNT8A using WNT8A Recombinant Monoclonal Antibody (Product # MA5-50327) in Mock and transfected 293T cells at a dilution of 1:500. Cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Wnt8a stained by Wnt8a antibody (MA5-50327) diluted at 1:500. Blue: Fluoroshield with DAPI.
Product Details
MA5-50327
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1648
Immunogen
Recombinant fragment of human Wnt8a.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
WNT8A, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: etID309727.14; Protein Wnt-8a; Protein Wnt-8d; wingless-type MMTV integration site family, member 8A; WNT8d
Gene Aliases: wnt-8; wnt8; wnt8.1; WNT8A; WNT8D; wu:fa20e02; wu:fe05d07
UniProt ID: (Human) Q9H1J5, (Zebrafish) P51028
Entrez Gene ID: (Human) 7478, (Zebrafish) 30122
eye development
mesoderm formation
mesodermal cell fate commitment
somitogenesis
multicellular organism development
ectoderm development
central nervous system development
endoderm development
mesoderm development
anterior/posterior pattern specification
dorsal/ventral pattern formation
positive regulation of gene expression
Wnt signaling pathway
spinal cord anterior/posterior patterning
neural plate anterior/posterior regionalization
neuron differentiation
hindbrain development
notochord development
brain segmentation
post-anal tail morphogenesis
cell proliferation involved in pronephros development
cell migration involved in gastrulation
Wnt signaling pathway involved in dorsal/ventral axis specification
cell fate commitment
positive regulation of fibroblast growth factor receptor signaling pathway
determination of dorsal identity
Spemann organizer formation
canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
neural plate pattern specification
negative regulation of canonical Wnt signaling pathway
regulation of anterior head development
anterior/posterior axis specification
dorsal/ventral axis specification
neural crest cell fate commitment
response to retinoic acid
positive regulation of transcription from RNA polymerase II promoter
secondary palate development
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support