Search

  • Fale Conosco
  • Pedido rápido

Invitrogen

Phospho-PKC alpha/delta (Thr410) Recombinant Rabbit Monoclonal Antibody (5W5G1)

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
Phospho-PKC alpha/delta (Thr410) Recombinant Rabbit Monoclonal Antibody (5W5G1)

Product Details

MA5-55196

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:3,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

5W5G1

Immunogen

A synthetic phosphorylated peptide around T410 of human PRKCZ.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.41 mg/mL

Amount

141 µg

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

RRID

AB_3667441

Product Specific Information

Immunogen Sequence: TTSTFC

Target Information

PKC alpha/delta refers to the protein kinase C isoforms alpha and delta, which are gene targets involved in various cellular processes and signaling pathways. Protein kinase C (PKC) is a family of enzymes that play a crucial role in regulating cell growth, differentiation, and intracellular signaling. PKC alpha and delta isoforms are widely expressed in different tissues and have distinct functions. PKC alpha is involved in cell proliferation, apoptosis, and cell cycle regulation, while PKC delta is implicated in cellular responses to stress, DNA damage, and apoptosis. These isoforms are activated by various stimuli, including second messengers and receptor-mediated signaling, leading to the phosphorylation of downstream targets and modulation of cellular processes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: AAG6; aging-associated gene 6; nPKC-delta; PKC-A; PKCA; PKCdeltaVIII; PRKACA; Protein kinase C; Protein kinase C alpha type; protein kinase C alpha-polypeptide; Protein kinase C delta type; protein kinase C delta VIII; Tyrosine-protein kinase PRKCD; unnamed protein product

View more View less

Gene Aliases: AAG6; ALPS3; CVID9; MAY1; nPKC-delta; PKC-alpha; PKCA; PKCalpha; PKCD; PKCI+/-; PRKACA; PRKCA; PRKCD

View more View less

UniProt ID: (Human) P17252, (Human) Q05655

View more View less

Entrez Gene ID: (Human) 5578, (Human) 5580

View more View less

Function(s)
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein kinase C activity calcium-dependent protein kinase C activity receptor binding integrin binding protein binding ATP binding zinc ion binding kinase activity transferase activity enzyme binding diacylglycerol binding histone kinase activity (H3-T6 specific) metal ion binding protein serine kinase activity calcium-independent protein kinase C activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity enzyme activator activity protein kinase binding protein tyrosine kinase activator activity insulin receptor substrate binding
Process(es)
response to reactive oxygen species angiogenesis positive regulation of endothelial cell proliferation desmosome assembly chromatin remodeling protein phosphorylation apoptotic process mitotic nuclear envelope disassembly cell adhesion learning or memory response to mechanical stimulus response to toxic substance positive regulation of signal transduction positive regulation of endothelial cell migration positive regulation of cardiac muscle hypertrophy negative regulation of translation central nervous system neuron axonogenesis signal transduction involved in regulation of gene expression positive regulation of cell migration positive regulation of lipopolysaccharide-mediated signaling pathway positive regulation of insulin secretion response to estradiol negative regulation of glial cell apoptotic process intracellular signal transduction proteasome-mediated ubiquitin-dependent protein catabolic process response to peptide hormone regulation of mRNA stability protein kinase B signaling positive regulation of blood vessel endothelial cell migration response to ethanol positive regulation of macrophage differentiation positive regulation of angiogenesis positive regulation of bone resorption positive regulation of cell adhesion positive regulation of exocytosis positive regulation of mitotic cell cycle positive regulation of smooth muscle cell proliferation regulation of transport response to corticosterone positive regulation of protein kinase B signaling positive regulation of synapse assembly renal sodium ion absorption positive regulation of ERK1 and ERK2 cascade protein kinase C signaling response to interleukin-1 regulation of platelet aggregation apoptotic signaling pathway positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of angiotensin-activated signaling pathway negative regulation of cytokine production involved in inflammatory response positive regulation of cytokine production involved in inflammatory response response to phorbol 13-acetate 12-myristate positive regulation of dense core granule biogenesis cellular response to DNA damage stimulus signal transduction intrinsic apoptotic signaling pathway in response to oxidative stress immunoglobulin mediated immune response peptidyl-serine phosphorylation peptidyl-threonine phosphorylation termination of signal transduction negative regulation of actin filament polymerization positive regulation of endodeoxyribonuclease activity positive regulation of superoxide anion generation regulation of actin cytoskeleton organization cellular response to UV Fc-gamma receptor signaling pathway involved in phagocytosis B cell proliferation neutrophil activation positive regulation of protein import into nucleus defense response to bacterium negative regulation of apoptotic process negative regulation of MAPK cascade post-translational protein modification negative regulation of insulin receptor signaling pathway negative regulation of inflammatory response protein stabilization positive regulation of DNA metabolic process negative regulation of filopodium assembly cell chemotaxis cellular response to hydrogen peroxide cellular response to fatty acid cellular response to hydroperoxide negative regulation of platelet aggregation cellular senescence phospholipase C/protein kinase C signal transduction positive regulation of phospholipid scramblase activity cellular response to angiotensin regulation of ceramide biosynthetic process positive regulation of ceramide biosynthetic process positive regulation of glucosylceramide catabolic process positive regulation of sphingomyelin catabolic process positive regulation of apoptotic signaling pathway
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support