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Invitrogen
Histone H2B Recombinant Rabbit Monoclonal Antibody (24GB3315)
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FIGURE: 1 / 2
Histone H2B Antibody (MA5-57035) in ICC/IF
Immunocytochemical staining of Histone H2B in HepG2 cells using Histone H2B Recombinant Monoclonal Antibody (Product # MA5-57035) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; Histone H2B was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Product Details
MA5-57035
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB3315
Immunogen
A synthesized peptide derived from human Histone H2B (aa 100-126)
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acetyl-Histone H2; H2B 291A; H2B 291B; H2b 613; H2B GL105 antibody; H2B histone family member M; H2B histone family member W testis-specific; H2B histone family member W, testis specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member S; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B K; H2B type 12; h2B-143; h2B-221; H2B-clustered histone 17; H2B-clustered histone 18; H2B-clustered histone 21; H2B-clustered histone 26; H2B-clustered histone 3; H2B-clustered histone 5; H2B-clustered histone 9; H2B.1 antibody; H2B.E variant histone 1; H2B.M histone; H2B.U histone 1; H2B.W histone 1; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/q; H2B/r; H2B/s; H2BK12ac; H2BK15ac; H2BK5ac; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRA-interacting protein 2; HIST1H2BB antibody; HIST1H3I; HIST2H2BE; histone 1, H2ba; histone 1, H2bb; histone 1, H2bc; histone 1, H2bd; histone 1, H2bg; histone 1, H2bh; histone 1, H2bi; histone 1, H2bj; histone 1, H2bk; histone 1, H2bl; histone 1, H2bm; histone 1, H2bn; histone 1, H2bo; histone 2, H2be; Histone 2B; histone 3, H2bb; histone cluster 1 H2B family member a; histone cluster 1 H2B family member b; histone cluster 1 H2B family member c; histone cluster 1 H2B family member d; histone cluster 1 H2B family member g; histone cluster 1 H2B family member h; histone cluster 1 H2B family member i; histone cluster 1 H2B family member j; histone cluster 1 H2B family member k; histone cluster 1 H2B family member l; histone cluster 1 H2B family member m; histone cluster 1 H2B family member n; histone cluster 1 H2B family member o; histone cluster 1, H2ba; histone cluster 1, H2bb; histone cluster 1, H2bc; histone cluster 1, H2bd; histone cluster 1, H2bg; histone cluster 1, H2bh; histone cluster 1, H2bi; histone cluster 1, H2bj; histone cluster 1, H2bk; histone cluster 1, H2bl; histone cluster 1, H2bm; histone cluster 1, H2bn; histone cluster 1, H2bo; histone cluster 2 H2B family member e; histone cluster 2 H2B family member f; histone cluster 2, H2be; histone cluster 2, H2bf; histone cluster 3 H2B family member b; histone cluster 3, H2bb; histone family member; histone H2B; Histone H2B type 1-A; Histone H2B type 1-B; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-C/E/G; Histone H2B type 1-D; Histone H2B type 1-F/J/L; Histone H2B type 1-H; Histone H2B type 1-J; Histone H2B type 1-K; Histone H2B type 1-L; Histone H2B type 1-M; Histone H2B type 1-N; Histone H2B type 1-O; Histone H2B type 2-E; Histone H2B type 2-E1; Histone H2B type 2-F; Histone H2B type 2-K1; Histone H2B type 3-B; Histone H2B type F-M; Histone H2B type W-T; Histone H2B, testis; Histone H2B-GL105; Histone H2B.1; Histone H2B.1 A; Histone H2B.1 B; Histone H2B.2; Histone H2B.a; Histone H2B.b; Histone H2B.c; Histone H2B.d; Histone H2B.e; Histone H2B.f; Histone H2B.g; Histone H2B.h; Histone H2B.I; Histone H2B.j; Histone H2B.k; Histone H2B.l; Histone H2B.n; Histone H2B.q; Histone H2B.r; Histone H2B.s; MGC125414; MGC125415; MGC125416; MGC9388; novel histone H2B-like protein; RP1-193B12.10; testis-specific histone 2b; Testis-specific histone H2B; TSH2B.1; unnamed protein product
Gene Aliases: 2610022J01Rik; AV127319; bA317E16.3; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; GL105; H2B; H2b-143; H2b-221; H2b-291b; H2b-613; H2b-f; H2B-GL105; H2b-j; H2b-l; H2b-n; H2B.1; H2B.1A; H2B.1B; H2B.2; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/j; H2B/k; H2B/l; H2B/n; H2B/r; H2B/S; H2Bb; H2BC1; H2BC10; H2BC11; H2BC12; H2BC13; H2BC14; H2BC15; H2BC17; H2BC18; H2BC21; H2BC26; H2BC3; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2BC9; H2BE; H2BE1; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFQ; H2BFR; H2bfs; H2BFT; H2BFU; H2BFWT; H2BGL105; H2BJ; H2BK; H2BK1; H2BM; H2BQ; H2BU1; H2BW1; H2BW2; HIRIP1; HIRIP2; HIST1H2BA; HIST1H2BB; HIST1H2BC; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BH; HIST1H2BI; HIST1H2BJ; HIST1H2BK; HIST1H2BL; HIST1H2BM; HIST1H2BN; HIST1H2BO; HIST2H2BE; HIST2H2BF; HIST3H2BB; hTSH2B; R74621; STBP; T25626; TH2B; TH2B-175; TSH2B; TSH2B.1
UniProt ID: (Human) Q96A08, (Human) P62807, (Human) P06899, (Human) O60814, (Human) Q99880, (Human) Q99879, (Human) Q99877, (Human) P23527, (Human) Q5QNW6, (Human) Q16778, (Human) Q8N257, (Human) P33778, (Human) Q93079, (Human) A0A2R8Y619, (Human) Q7Z2G1, (Human) P0C1H6, (Rat) Q00729, (Mouse) P70696, (Mouse) Q64475, (Mouse) Q6ZWY9, (Mouse) Q64478, (Mouse) P10853, (Mouse) Q8CGP1, (Mouse) P10854, (Mouse) Q64524
Entrez Gene ID: (Human) 255626, (Human) 8346, (Human) 8970, (Human) 85236, (Human) 8340, (Human) 8342, (Human) 8341, (Human) 8348, (Human) 440689, (Human) 8349, (Human) 128312, (Human) 3018, (Human) 8347, (Human) 3017, (Human) 8339, (Human) 8345, (Human) 114483833, (Human) 158983, (Human) 286436, (Rat) 24829, (Mouse) 319177, (Mouse) 319178, (Mouse) 68024, (Rat) 361247, (Mouse) 319181, (Mouse) 319182, (Mouse) 319183, (Mouse) 319184, (Rat) 680312, (Mouse) 319186, (Rat) 291157, (Mouse) 319190, (Rat) 691488, (Human) 102724334
chromatin organization
nucleosome assembly
nucleosome disassembly
inflammatory response
plasminogen activation
sperm chromatin condensation
chromosome organization
mononuclear cell migration
innate immune response in mucosa
antibacterial humoral response
defense response to bacterium
defense response to Gram-positive bacterium
antimicrobial humoral immune response mediated by antimicrobial peptide
negative regulation of tumor necrosis factor-mediated signaling pathway
killing of cells of other organism
defense response to Gram-negative bacterium
protein localization to CENP-A containing chromatin
mitotic chromosome condensation
spermatogenesis, exchange of chromosomal proteins
positive regulation of binding
cellular response to acid chemical
biological_process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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