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Invitrogen
CD94 Monoclonal Antibody (HP-3D9), PE
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FIGURE: 1 / 5
CD94 Antibody (MA562360) in Flow
Flow cytometry (expression profiling) of CD94 in peripheral blood subsets. Samples were stained with CD94 monoclonal antibody (Product # MA562360) using a dilution of 1 µg/mL. Adaptive panel. HCDM CDMaps standardized procedures were used for cell isolation and surface staining of blood leukocytes, with the modification of staining protocol using cytometry test tubes. Suspension of blood leukocytes isolated from buffy coats (2 x 10^6 cells) was added to the mixture of anti-human CD94 PE antibody (HP-3D9) and Monocyte Blocking Buffer, vortex... View More
Product Details
MA562360
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
HP-3D9
Immunogen
Cultured human NK cells.
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Purification
Size-exclusion chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
15mM sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Natural killer (NK) cells, like CD94, are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD94; CD94 antigen; Killer cell lectin-like receptor subfamily D member 1; killer cell lectin-like receptor subfamily D, member 1; KLRD1; KP43; natural killer cell receptor; Natural killer cells antigen CD94; NK cell receptor; unnamed protein product
Gene Aliases: CD94; KLRD1
UniProt ID: (Human) Q13241
Entrez Gene ID: (Human) 3824
negative regulation of T cell mediated cytotoxicity
stimulatory C-type lectin receptor signaling pathway
natural killer cell mediated immunity
adaptive immune response
immune system process
cell surface receptor signaling pathway
regulation of natural killer cell activation
innate immune response
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
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